Background: Rapid urbanization has led to emergence of squatter settlements with poor infrastructure and compromised basic amenities. These conditions expose vulnerable groups like women and children to serious health risks. This paper presents the status of maternal and child health in a squatter settlement of Karachi. Methods: Health and Demographic Surveillance System was established in Sultanabad, a squatter settlement of Karachi. Households were eligible to be enrolled if there was a married woman of 15-49 years of age. Data on socio-demographic, maternal and child health indicators was collected during a round of surveillance using a structured questionnaire adapted from Measure Demographic and Health Survey Phase III and Pakistan Dem...