The pregnant female human angiotensinogen (hAGN) transgenic rat mated with the male hrenin (hREN) transgenic rat is a model of preeclampsia with increased blood pressure, proteinuria, and placenta alterations of edema and necrosis. The reverse mating of female hRENxmale hAGN does not show preeclamptic features. Because the placenta is well-recognized to be a key contributor to the preeclamptic syndrome, our hypothesis is that local angiotensin peptide concentrations found in the placenta and its associated mesometrial triangle of the preeclamptic transgenic rat differ from the reverse mating. We characterized the angiotensin peptide content and the mRNA expression of hREN and hAGN of the mesometrial triangle and the placenta. Three groups o...
OBJECTIVE: Formerly preeclamptic women have an increased risk for cardiovascular and renal disease l...
International audienceGestational hypertensive disorders, such as preeclampsia, affect 6% to 8% of a...
We investigated intrauterine growth restriction, endothelial function, and uterine artery blood flow...
The pregnant female human angiotensinogen (hAGN) transgenic rat mated with the male hrenin (hREN) tr...
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the r...
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the r...
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the r...
Abstract—We used rats transgenic for the human angiotensinogen (hAogen) gene and the human renin (hR...
We used rats transgenic for the human angiotensinogen (hAogen) gene and the human renin (hRen) gene ...
The pregnant female human angiotensinogen (hAGN) transgenic rat mated with the male human renin (hRE...
Objective: Formerly preeclamptic women have an increased risk for cardiovascular and renal disease l...
Objective: Formerly preeclamptic women have an increased risk for cardiovascular and renal disease l...
Objective: Formerly preeclamptic women have an increased risk for cardiovascular and renal disease l...
First published April 20, 2012; doi:10.1152/ajpheart.00117.2012.—Preeclampsia is de-fined as new-ons...
Hypertensive disorders of pregnancy are the second leading cause of maternal deaths worldwide. Super...
OBJECTIVE: Formerly preeclamptic women have an increased risk for cardiovascular and renal disease l...
International audienceGestational hypertensive disorders, such as preeclampsia, affect 6% to 8% of a...
We investigated intrauterine growth restriction, endothelial function, and uterine artery blood flow...
The pregnant female human angiotensinogen (hAGN) transgenic rat mated with the male hrenin (hREN) tr...
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the r...
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the r...
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the r...
Abstract—We used rats transgenic for the human angiotensinogen (hAogen) gene and the human renin (hR...
We used rats transgenic for the human angiotensinogen (hAogen) gene and the human renin (hRen) gene ...
The pregnant female human angiotensinogen (hAGN) transgenic rat mated with the male human renin (hRE...
Objective: Formerly preeclamptic women have an increased risk for cardiovascular and renal disease l...
Objective: Formerly preeclamptic women have an increased risk for cardiovascular and renal disease l...
Objective: Formerly preeclamptic women have an increased risk for cardiovascular and renal disease l...
First published April 20, 2012; doi:10.1152/ajpheart.00117.2012.—Preeclampsia is de-fined as new-ons...
Hypertensive disorders of pregnancy are the second leading cause of maternal deaths worldwide. Super...
OBJECTIVE: Formerly preeclamptic women have an increased risk for cardiovascular and renal disease l...
International audienceGestational hypertensive disorders, such as preeclampsia, affect 6% to 8% of a...
We investigated intrauterine growth restriction, endothelial function, and uterine artery blood flow...