Status of genetic disorders among indigenous and crossbred breeding bulls in India

138-140In the present investigation, screening of genetic disorders, viz., Bovine leukocyte adhesion deficiency (BLAD), Deficiency of uridine monophosphate synthase (DUMPS), Bovine citrullinemia (BC) and Factor XI deficiency (FXID), was carried out in 438 bulls of exotic and indigenous breeds, viz., Holstein Friesian, Jersey, Khillar, Deoni and Malnad Gidda, using PCR based techniques. Of all bulls screened, two Holstein Friesian bulls were found to be the carrier for BLAD. None of the bulls screened was found to be the carriers of DUMPS, BC and FXID. Though the frequency of unfavorable allele was very low or nil, considering the economic and lethal impact of the diseases, it is recommended to screen the bulls intended for breeding purpose for genetic disorders to minimize the spread of defective alleles in the population