In the future, safety in historical city centers will be significantly affected by climate change-related disasters, such as floods. Risk assessment in these scenarios requires the combination of a series of factors: possible events characterization; urban layout configuration, its influence on flooding spreading and induced environmental modification; human factor, especially during first emergency phases. Historic urban scenario features (e.g.: compact urban fabrics; position near floodplains; possible inefficient early warning systems) additionally increase individuals’ risks. According to a “behavioral design” approach, developing flood evacuation simulation tools would help safety designers in assessing population’s exposure and then i...