We report the discovery with the Atacama Pathfinder EXperiment (APEX) of an outflow of molecular gas in the radio-loud Seyfert galaxy IC 5063 (z = 0.0110). In addition to the emission of the large-scale CO disk, a prominent blueshifted wing is observed in the CO(2−1) spectrum. IC 5063 represents one of the best cases of a fast jet-driven H I (and ionized gas) outflow, which is located at the site of a radio-bright feature about 0.5 kpc from the nucleus. It is possible that the blueshifted part of the molecular gas is associated with this outflow and is accelerated by the interaction with the radio jet. The outflow of molecular gas is characterized by an H2 mass of the outflowing component of between 2.25 ± 0.70 × 107M⊙ and 1.29 ± 0.40 × 108...