A stereoselective construction of the C21-C42 fragment 2 of rapamycin 1via coupling and elaboration of key intermediates 3-6 is described
An advanced intermediate in a projected synthesis of pactamycin has been prepared. Early installatio...
The macrolide rapamycin ( 1 ) was first described as an antifungal agent in 1975. Even though its bi...
The effective syntheses of the enantiomerically pure C1-C17 2 and C18-C25 3 fragments as promising s...
A strategy for a total synthesis of the immunosuppressant agent rapamycin 1 is outlined and the ster...
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described
This dissertation describes a stereoselective synthesis of two major fragments of rapamycin. Isolate...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
An efficient and convergent synthesis of the C<sub>5</sub>–C<sub>18</sub> fragment of halichomycin i...
This dissertation describes synthetic studies culminating in the total synthesis of the macrocyclic ...
Stereoselective synthesis of a peptidomimetic analog of the binding domain of rapamycin starting fro...
Details of the total synthesis of rapamycin (1) are reported. The synthesis required the preparation...
An efficient and convergent synthesis of the C-5-C-18 fragment of halichomycin is reported. Butanoli...
Researchers have long recognized the important physical relationship between molecular conformation ...
A novel synthetic approach towards the stereoselective synthesis of the C6-C18 fragment of the biolo...
An advanced intermediate in a projected synthesis of pactamycin has been prepared. Early installatio...
The macrolide rapamycin ( 1 ) was first described as an antifungal agent in 1975. Even though its bi...
The effective syntheses of the enantiomerically pure C1-C17 2 and C18-C25 3 fragments as promising s...
A strategy for a total synthesis of the immunosuppressant agent rapamycin 1 is outlined and the ster...
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described
This dissertation describes a stereoselective synthesis of two major fragments of rapamycin. Isolate...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
An efficient and convergent synthesis of the C<sub>5</sub>–C<sub>18</sub> fragment of halichomycin i...
This dissertation describes synthetic studies culminating in the total synthesis of the macrocyclic ...
Stereoselective synthesis of a peptidomimetic analog of the binding domain of rapamycin starting fro...
Details of the total synthesis of rapamycin (1) are reported. The synthesis required the preparation...
An efficient and convergent synthesis of the C-5-C-18 fragment of halichomycin is reported. Butanoli...
Researchers have long recognized the important physical relationship between molecular conformation ...
A novel synthetic approach towards the stereoselective synthesis of the C6-C18 fragment of the biolo...
An advanced intermediate in a projected synthesis of pactamycin has been prepared. Early installatio...
The macrolide rapamycin ( 1 ) was first described as an antifungal agent in 1975. Even though its bi...
The effective syntheses of the enantiomerically pure C1-C17 2 and C18-C25 3 fragments as promising s...