A strategy for a total synthesis of the immunosuppressant agent rapamycin 1 is outlined and the stereoselective construction of a suitably functionalized C8–C18 fragment 2 is described
Researchers have long recognized the important physical relationship between molecular conformation ...
Possible new immunosuppressants through biosynthesis: Derivatives of the immunosuppressant rapamycin...
Details of the total synthesis of rapamycin (1) are reported. The synthesis required the preparation...
A stereoselective construction of the C21-C42 fragment 2 of rapamycin 1via coupling and elaboration ...
This dissertation describes a stereoselective synthesis of two major fragments of rapamycin. Isolate...
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described
This dissertation describes synthetic studies culminating in the total synthesis of the macrocyclic ...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
For over 30 years, rapamycin has generated a sustained and intense interest from the scientific comm...
An efficient and convergent synthesis of the C<sub>5</sub>–C<sub>18</sub> fragment of halichomycin i...
A novel synthetic approach towards the stereoselective synthesis of the C6-C18 fragment of the biolo...
Stereoselective synthesis of a peptidomimetic analog of the binding domain of rapamycin starting fro...
The macrolide rapamycin ( 1 ) was first described as an antifungal agent in 1975. Even though its bi...
An efficient and convergent synthesis of the C-5-C-18 fragment of halichomycin is reported. Butanoli...
Researchers have long recognized the important physical relationship between molecular conformation ...
Possible new immunosuppressants through biosynthesis: Derivatives of the immunosuppressant rapamycin...
Details of the total synthesis of rapamycin (1) are reported. The synthesis required the preparation...
A stereoselective construction of the C21-C42 fragment 2 of rapamycin 1via coupling and elaboration ...
This dissertation describes a stereoselective synthesis of two major fragments of rapamycin. Isolate...
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described
This dissertation describes synthetic studies culminating in the total synthesis of the macrocyclic ...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
For over 30 years, rapamycin has generated a sustained and intense interest from the scientific comm...
An efficient and convergent synthesis of the C<sub>5</sub>–C<sub>18</sub> fragment of halichomycin i...
A novel synthetic approach towards the stereoselective synthesis of the C6-C18 fragment of the biolo...
Stereoselective synthesis of a peptidomimetic analog of the binding domain of rapamycin starting fro...
The macrolide rapamycin ( 1 ) was first described as an antifungal agent in 1975. Even though its bi...
An efficient and convergent synthesis of the C-5-C-18 fragment of halichomycin is reported. Butanoli...
Researchers have long recognized the important physical relationship between molecular conformation ...
Possible new immunosuppressants through biosynthesis: Derivatives of the immunosuppressant rapamycin...
Details of the total synthesis of rapamycin (1) are reported. The synthesis required the preparation...
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