Add to ORKGAn enantioselective route to cis-perhydroisoquinolines, involving a cyclocondensation reaction of (R)-phenylglycinol with a racemic oxoester, a stereoselective conjugate addition to an unsaturated bicyclic lactam, and the closure of the carbocyclic ring by a ring-closing metathesis as the key steps is reported. This route allows the preparation of 3-cyano derivatives as well as cis-octahydroisoquinolines bearing a quaternary center at the C4-position
In situ-generated ortho-halogenated phenylmeth-animines coordinated to the tricarbonylchromium group...
The Bischler-Napieralski reaction, which is used to prepare dihydroisoquinolines from phenylethylami...
N-Acyl-N-(4-penten-1-yl)-1-amino-1, 3-butadiene (1) isomerisieren sich bei 190-215° über eine intram...
An enantioselective route to cis-perhydroisoquinolines, involving a cyclocondensation reaction of (R...
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted...
A practical synthetic route to enantiopure 5-substituted cisdecahydroquinolines has been developed, ...
Up to four stereocenters with a well-defined configuration are generated in a single synthetic step ...
Stereoconvergent cyclocondensation reactions of (R)- or (S)-phenylglycinol with appropriately substi...
Starting from the 8-allyl substituted oxazolopiperidone lactam 2b, which is easily accessible from (...
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted...
Stereoconvergent cyclocondensation reactions of (<i>R</i>)- or (<i>S</i>)-phenylglycinol with approp...
The straightforward enantioselective construction of the hydroquinoline ring system from 1,5-polycar...
Quaternary centers are rapidly and selectively installed in a series of seven-membered and bridged c...
The acid-promoted cyclizations of a range of N-benzylethanolamines (derived from pseudoephedrine or ...
Radical cyclizations (Bu3SnH, Et3B/air, rt) of racemic R-halo-ortho-alkenyl anilides provide 3,4-dih...
In situ-generated ortho-halogenated phenylmeth-animines coordinated to the tricarbonylchromium group...
The Bischler-Napieralski reaction, which is used to prepare dihydroisoquinolines from phenylethylami...
N-Acyl-N-(4-penten-1-yl)-1-amino-1, 3-butadiene (1) isomerisieren sich bei 190-215° über eine intram...
An enantioselective route to cis-perhydroisoquinolines, involving a cyclocondensation reaction of (R...
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted...
A practical synthetic route to enantiopure 5-substituted cisdecahydroquinolines has been developed, ...
Up to four stereocenters with a well-defined configuration are generated in a single synthetic step ...
Stereoconvergent cyclocondensation reactions of (R)- or (S)-phenylglycinol with appropriately substi...
Starting from the 8-allyl substituted oxazolopiperidone lactam 2b, which is easily accessible from (...
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted...
Stereoconvergent cyclocondensation reactions of (<i>R</i>)- or (<i>S</i>)-phenylglycinol with approp...
The straightforward enantioselective construction of the hydroquinoline ring system from 1,5-polycar...
Quaternary centers are rapidly and selectively installed in a series of seven-membered and bridged c...
The acid-promoted cyclizations of a range of N-benzylethanolamines (derived from pseudoephedrine or ...
Radical cyclizations (Bu3SnH, Et3B/air, rt) of racemic R-halo-ortho-alkenyl anilides provide 3,4-dih...
In situ-generated ortho-halogenated phenylmeth-animines coordinated to the tricarbonylchromium group...
The Bischler-Napieralski reaction, which is used to prepare dihydroisoquinolines from phenylethylami...
N-Acyl-N-(4-penten-1-yl)-1-amino-1, 3-butadiene (1) isomerisieren sich bei 190-215° über eine intram...