A practical synthetic route to enantiopure 5-substituted cisdecahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of 2-substituted 6-oxocyclohexenepropionates 2 with (R)-phenylglycinol, the stereoselective hydrogenation of the resulting unsaturated tricyclic lactams, and the stereoselective reductive cleavage of the oxazolidine ring
Cyclocondensation of (<i>R</i>)-phenylglycinol with stereoisomeric mixtures (racemates, <i>cis</i>/<...
[eng] The first objective of this Thesis was the study of the preparation of octhydro-1H-cyclopenta[...
A route for the preparation of 2,5-disubstituted octahydroquinolin-4-ones, synthetic precursors of t...
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted...
A practical synthetic route to enantiopure 5-substituted cisdecahydroquinolines has been developed, ...
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted...
Stereoconvergent cyclocondensation reactions of (R)- or (S)-phenylglycinol with appropriately substi...
Stereoconvergent cyclocondensation reactions of (<i>R</i>)- or (<i>S</i>)-phenylglycinol with approp...
An enantioselective route to cis-perhydroisoquinolines, involving a cyclocondensation reaction of (R...
Up to four stereocenters with a well-defined configuration are generated in a single synthetic step ...
Starting from the 8-allyl substituted oxazolopiperidone lactam 2b, which is easily accessible from (...
In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones,...
The straightforward enantioselective construction of the hydroquinoline ring system from 1,5-polycar...
Cyclocondensation of (R)-phenylglycinol with stereoisomeric mixtures (racemates, cis/trans) of 3-sub...
Approaches toward the syntheses of alkaloids belonging to the 2,6-disubstituted 3-hydroxypiperidine ...
Cyclocondensation of (<i>R</i>)-phenylglycinol with stereoisomeric mixtures (racemates, <i>cis</i>/<...
[eng] The first objective of this Thesis was the study of the preparation of octhydro-1H-cyclopenta[...
A route for the preparation of 2,5-disubstituted octahydroquinolin-4-ones, synthetic precursors of t...
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted...
A practical synthetic route to enantiopure 5-substituted cisdecahydroquinolines has been developed, ...
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted...
Stereoconvergent cyclocondensation reactions of (R)- or (S)-phenylglycinol with appropriately substi...
Stereoconvergent cyclocondensation reactions of (<i>R</i>)- or (<i>S</i>)-phenylglycinol with approp...
An enantioselective route to cis-perhydroisoquinolines, involving a cyclocondensation reaction of (R...
Up to four stereocenters with a well-defined configuration are generated in a single synthetic step ...
Starting from the 8-allyl substituted oxazolopiperidone lactam 2b, which is easily accessible from (...
In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones,...
The straightforward enantioselective construction of the hydroquinoline ring system from 1,5-polycar...
Cyclocondensation of (R)-phenylglycinol with stereoisomeric mixtures (racemates, cis/trans) of 3-sub...
Approaches toward the syntheses of alkaloids belonging to the 2,6-disubstituted 3-hydroxypiperidine ...
Cyclocondensation of (<i>R</i>)-phenylglycinol with stereoisomeric mixtures (racemates, <i>cis</i>/<...
[eng] The first objective of this Thesis was the study of the preparation of octhydro-1H-cyclopenta[...
A route for the preparation of 2,5-disubstituted octahydroquinolin-4-ones, synthetic precursors of t...