In this study we investigate how the basal ganglia (BG) may process the behavioural relevance of environmental cues by recording local field potentials (LFPs) in the subthalamic nucleus of patients with Parkinson’s disease who had undergone implantation of electrodes for deep brain stimulation. Fourteen patients were recorded as they performed a paradigm dissociating warning cue presentation from programming related to execution of specific tasks. Target and non-target warning cues of differing behavioural relevance were contrasted, and we evaluated if warning cue-evoked activities varied according to whether the eventual task to be performed was motor or cognitive and whether patients were receiving or withdrawn from dopaminergic therapy. ...
<div><p>A fundamental function of the motor system is to gather key information from the environment...
Subthalamic deep brain stimulation (STN-DBS) for Parkinson's disease treats motor symptoms and impro...
Cognitive and behavioural disturbances in patients with Parkinson’s disease seem to be relatively m...
In this study we investigate how the basal ganglia (BG) may process the behavioural relevance of env...
In this study we investigate how the basal ganglia (BG) may process the behavioural relevance of env...
The speed with which one reacts to an imperative signal depends on the extent to which preceding cue...
Adapting actions to changing goals and environments is central to intelligent behavior. There is evi...
Adapting our actions to changing goals and environments is central to intelligent behavior. There is...
Deep brain stimulation of the subthalamic nucleus is an established treatment for the motor symptom...
International audienceOscillatory activity in the beta frequency band has been shown to be modulated...
Visual cues open a unique window to the understanding of Parkinson's disease (PD). These cues can te...
The behavioral implications of deep brain stimulation (DBS) observed in Parkinson's disease patients...
Movement is accompanied by changes in the degree to which neurons in corticobasal ganglia loops sync...
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Neurobiology and A...
Implantation of deep brain stimulation (DBS) electrodes via stereotactic neurosurgery has become a s...
<div><p>A fundamental function of the motor system is to gather key information from the environment...
Subthalamic deep brain stimulation (STN-DBS) for Parkinson's disease treats motor symptoms and impro...
Cognitive and behavioural disturbances in patients with Parkinson’s disease seem to be relatively m...
In this study we investigate how the basal ganglia (BG) may process the behavioural relevance of env...
In this study we investigate how the basal ganglia (BG) may process the behavioural relevance of env...
The speed with which one reacts to an imperative signal depends on the extent to which preceding cue...
Adapting actions to changing goals and environments is central to intelligent behavior. There is evi...
Adapting our actions to changing goals and environments is central to intelligent behavior. There is...
Deep brain stimulation of the subthalamic nucleus is an established treatment for the motor symptom...
International audienceOscillatory activity in the beta frequency band has been shown to be modulated...
Visual cues open a unique window to the understanding of Parkinson's disease (PD). These cues can te...
The behavioral implications of deep brain stimulation (DBS) observed in Parkinson's disease patients...
Movement is accompanied by changes in the degree to which neurons in corticobasal ganglia loops sync...
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Neurobiology and A...
Implantation of deep brain stimulation (DBS) electrodes via stereotactic neurosurgery has become a s...
<div><p>A fundamental function of the motor system is to gather key information from the environment...
Subthalamic deep brain stimulation (STN-DBS) for Parkinson's disease treats motor symptoms and impro...
Cognitive and behavioural disturbances in patients with Parkinson’s disease seem to be relatively m...