Pre-Chemotherapy risk factors for invasive fungal diseases: Prospective analysis of 1,192 patients with newly diagnosed acute myeloid leukemia (seifem 2010-a multicenter study)
- Caira M.
- Candoni A.
- Verga L.
- Busca A.
- Delia M.
- Nosari A.
- Caramatti C.
- Castagnola C.
- Cattaneo C.
- Fanci R.
- Chierichini A.
- Melillo L.
- Mitra M. E.
- Picardi M.
- Potenza L.
- Salutari P.
- Vianelli N.
- Facchini L.
- Cesarini M.
- De Paolis M. R.
- Di Blasi R.
- Farina F.
- Venditti A.
- Ferrari A.
- Garzia M.
- Gasbarrino C.
- Invernizzi R.
- Lessi F.
- Manna A.
- Martino B.
- Nadali G.
- Offidani M.
- Paris L.
- Pavone V.
- Rossi G.
- Spadea A.
- Specchia G.
- Trecarichi E. M.
- Vacca A.
- Cesaro S.
- Perriello V.
- Aversa F.
- Tumbarello M.
- Pagano L.
- Ragionieri R.
- Orsola-Malpighi O. S.
- Antoniazzi F.
- Storti S.
- Luppi M.
- Pagliuca S.
- Rossetti E.
- Da Via M.
- Di Caprio L.
- Majolino I.
- Cascavilla N.
- Turri G.
- Fanin R.
DOIAbstract
Correct definition of the level of risk of invasive fungal infections is the first step in improving the targeting of preventive strategies. We investigated the potential relationship between pre-hospitalization exposure to sources of fungi and the development of invasive fungal infections in adult patients with newly diagnosed acute myeloid leukemia after their first course of chemotherapy. From January 2010 to April 2012, all consecutive acute myeloid leukemia patients in 33 Italian centers were prospectively registered. Upon first admission, information about possible pre-chemotherapy risk factors and environmental exposure was collected. We recorded data regarding comorbid conditions, employment, hygienic habits, working and living envi...
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