The increase of climate change effects is becoming a major challenge to be urgently tackled with a combination of measures that become particularly effective when deployed in a Smart Energy System context when positive interactions among sectors can be exploited to meet the challenging targets that are being set at different governance levels. Local energy planning strategies, relying on multi-level and integrated approaches, are needed to ensure that optimal solutions are developed according to specific resources and requirements of each region. With the help of EnergyPLAN software, this paper explores and compares possible future solutions for the decarbonization of an Alpine region in the North-East of Italy. Options for a sustainable an...