In this paper, a closed-form expression of a macroscopic strength criterion for ductile nanoporous materials is established, by considering the local plastic behavior as dependent on all the three isotropic stress invariants and by referring to the case of axisymmetric strain-rate boundary conditions. The proposed criterion also predicts void-size effects on macroscopic strength prop- erties. A homogenization procedure based on a kinematic limit-analysis is performed by addressing a hollow-sphere model comprising a rigid-ideal-plastic solid matrix. Void-size effects are accounted for by introducing an imperfect-coherent interface at the cavity boundary. Both the interface and the solid matrix are assumed to obey to a general isotropic yield...