Strategies to govern systemic risk are reviewed and the potential of systems analysis to address these challenges is assessed. OECD and IIASA’s approaches are described. A fundamental challenge to governing systemic risk is understanding the system as a complex network of individual and institutional actors with different and often conflicting interests, values and worldviews. Superimposed on this governance network are the potential risk events with ill-defined chains or networks of interrelated consequences and impacts. The importance of applying a systems approach to both the system to be governed and the governance system is emphasised. The OECD’s ‘whole of society’ approach for managing risk could incorporate IIASA’s suggestions for es...