We review recent mathematical models describing the diffusive transport, reaction, and turnover of actin and regulators at the leading edge of motile cells. These models are motivated by experimental results using cells with flat, steady lamellipodia studied by Single Molecule Speckle microscopy. The same cells can also be made to exhibit protruding and retracting lamellipodia, which demonstrate how changes in actin polymerization lead to changes in the rate of protrusion. The second part of this chapter provides a description of these fluctuations as an excitable actin system pushing against the cell membrane by polymerization
AbstractDuring cell motion on a substratum, eukaryotic cells project sheetlike lamellipodia which co...
AbstractMany animal cells initiate crawling by protruding lamellipodia, consisting of a dense networ...
The Filament Based Lamellipodium Model (FBLM) is a two-phase two-dimensional continuum model, descri...
We review recent mathematical models describing the diffusive transport, reaction, and turnover of a...
Cell motility driven by actin polymerization is pivotal to the development and survival of organisms...
Animal cells that spread onto a surface often rely on actin‐rich lamellipodial extensions to execute...
Animal cells that spread onto a surface often rely on actin‐rich lamellipodial extensions to execute...
Animal cells that spread onto a surface often rely on actin-rich cell extensions called lamellipodia...
Animal cells that spread onto a surface often rely on actin-rich cell extensions called lamellipodia...
ABSTRACT A motile cell, when stimulated, shows a dramatic increase in the activity of its membrane, ...
AbstractStudies of actin dynamics at the leading edge of motile cells with single-molecule speckle (...
AbstractA motile cell, when stimulated, shows a dramatic increase in the activity of its membrane, m...
AbstractMany animal cells initiate crawling by protruding lamellipodia, consisting of a dense networ...
Cell motility driven by actin polymerization is pivotal to the development and survival of organisms...
AbstractWe develop a mathematical model that describes key details of actin dynamics in protrusion a...
AbstractDuring cell motion on a substratum, eukaryotic cells project sheetlike lamellipodia which co...
AbstractMany animal cells initiate crawling by protruding lamellipodia, consisting of a dense networ...
The Filament Based Lamellipodium Model (FBLM) is a two-phase two-dimensional continuum model, descri...
We review recent mathematical models describing the diffusive transport, reaction, and turnover of a...
Cell motility driven by actin polymerization is pivotal to the development and survival of organisms...
Animal cells that spread onto a surface often rely on actin‐rich lamellipodial extensions to execute...
Animal cells that spread onto a surface often rely on actin‐rich lamellipodial extensions to execute...
Animal cells that spread onto a surface often rely on actin-rich cell extensions called lamellipodia...
Animal cells that spread onto a surface often rely on actin-rich cell extensions called lamellipodia...
ABSTRACT A motile cell, when stimulated, shows a dramatic increase in the activity of its membrane, ...
AbstractStudies of actin dynamics at the leading edge of motile cells with single-molecule speckle (...
AbstractA motile cell, when stimulated, shows a dramatic increase in the activity of its membrane, m...
AbstractMany animal cells initiate crawling by protruding lamellipodia, consisting of a dense networ...
Cell motility driven by actin polymerization is pivotal to the development and survival of organisms...
AbstractWe develop a mathematical model that describes key details of actin dynamics in protrusion a...
AbstractDuring cell motion on a substratum, eukaryotic cells project sheetlike lamellipodia which co...
AbstractMany animal cells initiate crawling by protruding lamellipodia, consisting of a dense networ...
The Filament Based Lamellipodium Model (FBLM) is a two-phase two-dimensional continuum model, descri...