Atrial Fibrillation (AF) is the most common arrhythmia. It is associated with increased cardiovascular morbidity and mortality, and exposes patients to a strongly increased risk of stroke. AF is resistant to antiarrhythmic drugs, making it a significant public health problem. At an early stage, AF is due to abnormal electric foci located in the myocardial sleeves of pulmonary veins (PV). The mechanism initiating these ectopic foci is unknown. Calcium (Ca 2+ ) being frequently involved in the triggering of pro-arrhythmic electric signals, we thus hypothesized that it could also be involved in the arrhythmias occurring in the PV sleeves.Structural and functional features of the calcium cycle are unknown in PV cardiomyocytes (CM). Therefore, w...
Aortic stenosis (AS) is the most common valvular heart disease (VHD) in Western countries. It causes...
Obstructive sleep apnea syndrome (OSAS) is a chronic disease characterized by repeated interruptions...
La dépolarisation de la membrane plasmique des cellules musculaires provoque, par un mécanisme mal c...
Atrial Fibrillation (AF) is the most common arrhythmia. It is associated with increased cardiovascul...
Atrial fibrillation (AF) is the most common cardiac arrhythmia in humans and is associated with incr...
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal genetic arrhythmia that man...
The right ventricle (RV) and more specifically the RV outflow tract, is a common anatomical origin o...
A first part of the thesis allowed the establishment of a protocol for cardiomyocytes isolation from...
Heart failure (HF) is the final outcome of several chronic diseases that affect the heart function, ...
Résumé: Le but de ce travail est de comprendre la modulation des canaux calciques cardiaques par les...
Résumé: Le but de ce travail est de comprendre la modulation des canaux calciques cardiaques par les...
In this chapter we will briefly review the structure, physiology and pathophysiology of the cardiac ...
In this chapter we will briefly review the structure, physiology and pathophysiology of the cardiac ...
Introduction: The L-type cardiac Ca2+ channel (Cav 1.2) is an important determinant of cardiac repol...
Aortic stenosis (AS) is the most common valvular heart disease (VHD) in Western countries. It causes...
Aortic stenosis (AS) is the most common valvular heart disease (VHD) in Western countries. It causes...
Obstructive sleep apnea syndrome (OSAS) is a chronic disease characterized by repeated interruptions...
La dépolarisation de la membrane plasmique des cellules musculaires provoque, par un mécanisme mal c...
Atrial Fibrillation (AF) is the most common arrhythmia. It is associated with increased cardiovascul...
Atrial fibrillation (AF) is the most common cardiac arrhythmia in humans and is associated with incr...
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal genetic arrhythmia that man...
The right ventricle (RV) and more specifically the RV outflow tract, is a common anatomical origin o...
A first part of the thesis allowed the establishment of a protocol for cardiomyocytes isolation from...
Heart failure (HF) is the final outcome of several chronic diseases that affect the heart function, ...
Résumé: Le but de ce travail est de comprendre la modulation des canaux calciques cardiaques par les...
Résumé: Le but de ce travail est de comprendre la modulation des canaux calciques cardiaques par les...
In this chapter we will briefly review the structure, physiology and pathophysiology of the cardiac ...
In this chapter we will briefly review the structure, physiology and pathophysiology of the cardiac ...
Introduction: The L-type cardiac Ca2+ channel (Cav 1.2) is an important determinant of cardiac repol...
Aortic stenosis (AS) is the most common valvular heart disease (VHD) in Western countries. It causes...
Aortic stenosis (AS) is the most common valvular heart disease (VHD) in Western countries. It causes...
Obstructive sleep apnea syndrome (OSAS) is a chronic disease characterized by repeated interruptions...
La dépolarisation de la membrane plasmique des cellules musculaires provoque, par un mécanisme mal c...