Being able to predict the fatigue resistance of parts produced by additive manufacturing (AM) is a very actual and frequent open issue. The qualification of AM structural parts needs a very costly and time consuming series of fatigue tests, on both samples and full-scale parts. A proper control of the AM process allows obtaining comparable and even better fatigue resistance than standard manufacturing. Despite this, the experimental results often show a large scatter, mostly due to the presence of defects. In this framework, this work summarizes a research activity aiming at modelling the high cycle fatigue (HCF) resistance in presence of defects, focusing on AlSi10Mg produced by selective laser melting (SLM). Two batches of samples were in...