The U.S. Centers for Disease Control and Prevention (CDC) began working in Senegal in 2001, supporting the HIV/Sexually Transmitted Infection sentinel surveillance program. Since 2010 through the President\u2019s Emergency Plan for AIDS Relief (PEPFAR), CDC has continued to support Senegal\u2019s Ministry of Health to build a sustainable and reliable national HIV surveillance system by developing a functioning HIV case reporting and surveillance system, strengthening the quality of routine prevention of mother-to-child transmission (PMTCT) of HIV data and on-site HIV rapid testing.Senegal\u2019s HIV epidemic is concentrated with an HIV prevalence of less than < 1% in the general population but very high (up to 20%) among certain key populat...