Floating Drug Delivery System: A comprehensive review

The recent literature with some special interest on the principal mechanism of floatation to obtain gastric retention is the main purpose of writing this review on floating drug delivery systems (FDDS). The recent developments in floating drug delivery systems are containing the physiological and formulation variables impacting on gastric retention time, approaches to formulating of single-unit and multiple-unit floating systems, and their classification and formulation aspects are discussed in detail. This review also summarizes evaluation parameters and application of floating drug delivery systems. These systems are useful to several problems introduced during the formulations of a pharmaceutical dosage form. Keywords: floating drug delivery system, gastro-retention, floating beads, gastric technology