Emissions of carbon monoxide (CO) from motor vehicles cause several hundred accidental fatal poisonings annually in the United States. The circumstances that could lead to fatal poisonings in residential settings with motor vehicles as the source of CO were explored. The risk of death in a garage (volume = 90 m3) and a single-family dwelling (400 m3) was evaluated using a Monte Carlo simulation with varying CO emission rates and ventilation rates. Information on emission rates was obtained from a survey of motor vehicle exhaust gas composition under warm idle conditions in California, and information on ventilation rates was obtained from a summary of published measurements in the U.S. housing stock. The risk of death ranged from 16 to 21% ...