Daun dewa dapat menghambat respon rasa nyeri

The use of herbal medicine has already been started since ancient time. According to Hembing, a consumption of Gynura segetum (Lour.) Merr.) stew water can be used to eliminate joint pain. The purpose of this study is to prove the analgesic effect of infusum Gynura segetum (Lour.) Merr.). The subject were thirty male mice and divided into five groups which consist six mice in each group. Group I was the control group which was treated with 0,01ml/g b.w aquadestilata, group II was treated with infusum of Gynura segetum (Lour.) Merr.) 5 % 0,01 ml/g b.w., group III was treated with infusum of Gynura segetum (Lour.) Merr.) 10 % 0,01 ml/g b.w, group IV was treated with infusum of Gynura segetum (Lour.) Merr.) 20 % 0,01 ml/g b.w. and group V was treated with Metampiron peroral 0,01 ml/g b.w. Thirty minutes later all mice of all groups were injected with 10 ml/g b.w. of acetic acid intraperitoneally to induced pain sensation. Five minutes later the writing reflexes as the pain response demonstrated by the mice of different groups were calculated and analysed using ANOVA and LSD test. The result showed that infusum Gynura segetum (Lour.) Merr.) in 5%, 10%, 20% concentration could obstruct pain response on mice which inducted with acetic acid, the 20% concentration is the most effective dosage and have an analgesic effects equal with metampiron