Comparative Study on the Analgesic Effect of Fresh Moringa Oleifera Juice with Ibuprofen in Albino Mice

This study was aimed to assess whether Moringa oleifera also have analgesic activity like NSAIDS. After animal ethics committee approval, this study was carried out. 6 male and 6 non pregnant female albino mice were used for the study. First they were given 1 % acetic acid intraperitonealy, noted for number of writhings over 20 minutes. A week later Ibuprofen was given orally and 30 minutes later acetic acid was injected and number of writhings were noted. After one week interval, same procedure was repeated with Moringa oleifera instead of Ibuprofen. The results were statistically analysed. From our study it was found that, (1). Among male and female mice, there is no significant difference in reduction number of writhings. This shows that Moringa Oleifera has equal pain lowering effect in both males and females. Both among males and female mice, Moringa has decreased number of writhings compared to controls. This shows that it has analgesic property. (2). Both among males and females, there is no difference in reduction of number of writhings between Moringa and Ibuprofen. This shows that both have equal analgesic property. (3). From this study we conclude that Moringa oleifera has got analgesic properties as that of Ibuprofen. Thus the use of Moringa oleifera extract in relieving muscle pain can be promoted in both indigenous and other local medicinal practices directed towards people of low socio economic status