The efficient preservation of masonry monuments presents several challenges given that they are characterized by much larger uncertainties than ordinary buildings and conventional analysis tools may fail in providing a reliable characterization of their structural behavior. A complete understanding of the structural behavior of masonry monuments requires integration of historical, topographical, structural, and geotechnical information. From 2010, an interdisciplinary committee has been established to study the Cathedral of Modena, a masterpiece of Romanesque architecture in Italy. Great effort has been devoted to the assessment of the structural health of the Cathedral, revealing that the vaults are the most vulnerable components,...