In this paper an experimental study conducted on fired-clay brick masonry triplets built with cement- and hydraulic lime-based mortars and subjected to artificial weathering cycles is presented. A cycle is constituted by (1) a wetting phase by capillary rise of either a saline solution or deionized water and (2) a drying phase in oven. The aim of the accelerate weathering cycles is to simulate on-site conditions of masonry structures subjected to rising damp and salts attack due to daily and seasonal microclimatic changes. For comparison purposes, triplets subjected to drying cycles only were also considered. At the end of the weathering process, the triplets were shear tested in order to quantitative assess the separate and combined effect...