In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherapeutic drugs. Nanotechnology offers the unique opportunity to overcome these barriers. In particular, in the last few years, DNA nanostructures have gained attention for their biocompatibility, easy customized synthesis and ability to deliver drugs to cancer cells. Here, an open-caged pyramidal DNA at Doxorubicin (Py-Doxo) nanostructure was constructed with 10 DNA sequences of 26-28 nucleotides for drug delivery to cancer cells. The synthesized DNA nanostructures are sufficiently stable in biological medium. Py-Doxo exhibited significantly enhanced cytotoxicity of the delivered doxorubicin to breast and liver cancer cells up to twofold compared...
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in ...
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in ...
Despite great progress in recent years, efficient delivery of gene therapy or chemotherapy drugs int...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the bi...
DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the bi...
DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the bi...
DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the bi...
By its unique advantages over traditional medicine, nanomedicine has offered new strategies for canc...
Objectives: Here, a novel cruciform DNA nanostructure was developed for targeted delivery of doxorub...
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in ...
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in ...
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in ...
Despite great progress in recent years, efficient delivery of gene therapy or chemotherapy drugs int...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
In cancer therapy, it is imperative to increase the efficacy and reduce side effects of chemotherape...
DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the bi...
DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the bi...
DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the bi...
DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the bi...
By its unique advantages over traditional medicine, nanomedicine has offered new strategies for canc...
Objectives: Here, a novel cruciform DNA nanostructure was developed for targeted delivery of doxorub...
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in ...
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in ...
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in ...
Despite great progress in recent years, efficient delivery of gene therapy or chemotherapy drugs int...