Stanniocalcin 1 (STC1) is a glycoprotein hormone expressed in different mammalian tissues. In previous studies, we showed STC1 expression in swine ovarian follicles and we demonstrated that STC1 may be a physiological regulator of follicular function. Since reactive oxygen species (ROS) are important signal transducers in the ovary, the present study was undertaken to investigate STC1 action on ROS generation and on the activity of the major enzymatic and non-enzymatic scavengers in swine granulosa cells. O2- generation, catalase activity and FRAP levels were increased by STC1, whereas H2O2 generation and peroxidase activity were decreased by STC1. Taken together, our data show that STC1 modulates redox status in swine granulosa cells
Sanguinarine (SA) has been used in toothpastes and oral rinse products and has been recently applied...
Inhibition of angiogenesis is an important new approach for cancer treatment and the research on thi...
Follicular growth is characterized by an augmented vascularization, possibly driven by a fall in the...
Stanniocalcin 1 (STC 1) is a glycoprotein involved in mineral homeostasis and was first identified i...
Granulosa cell steroidogenesis is partly regulated by intrafollicular events. Stanniocalcin 1 (STC1)...
The ovarian follicle represents an outstanding model for the investigation of the angiogenic process...
The ovarian follicle represents an outstanding model for the investigation of the angiogenic proces...
A growing body of evidence indicates that the pro-oxidant/anti-oxidant balance inside the ovarian f...
During follicle growth swine granulosa cells are physiologically exposed to a progressive oxygen sho...
The most characterized stromal cell-derived factor-1 (SDF-1) variants are the isoform α, which is th...
2-Methoxyestradiol (2-ME) is an estradiol metabolite with antiangiogenic properties. It can be produ...
In addition to the well-known central modulatory role of orexins, we recently demonstrated a periphe...
Hypoxia occurs physiologically during ovarian follicle growth; this deprivation represents a trigge...
Follicular growth is characterized by an augmented vascularization, possibly driven by a fall in the...
Stanniocalcin (STC) is a recently discovered mammalian hormone that is widely distributed in many ti...
Sanguinarine (SA) has been used in toothpastes and oral rinse products and has been recently applied...
Inhibition of angiogenesis is an important new approach for cancer treatment and the research on thi...
Follicular growth is characterized by an augmented vascularization, possibly driven by a fall in the...
Stanniocalcin 1 (STC 1) is a glycoprotein involved in mineral homeostasis and was first identified i...
Granulosa cell steroidogenesis is partly regulated by intrafollicular events. Stanniocalcin 1 (STC1)...
The ovarian follicle represents an outstanding model for the investigation of the angiogenic process...
The ovarian follicle represents an outstanding model for the investigation of the angiogenic proces...
A growing body of evidence indicates that the pro-oxidant/anti-oxidant balance inside the ovarian f...
During follicle growth swine granulosa cells are physiologically exposed to a progressive oxygen sho...
The most characterized stromal cell-derived factor-1 (SDF-1) variants are the isoform α, which is th...
2-Methoxyestradiol (2-ME) is an estradiol metabolite with antiangiogenic properties. It can be produ...
In addition to the well-known central modulatory role of orexins, we recently demonstrated a periphe...
Hypoxia occurs physiologically during ovarian follicle growth; this deprivation represents a trigge...
Follicular growth is characterized by an augmented vascularization, possibly driven by a fall in the...
Stanniocalcin (STC) is a recently discovered mammalian hormone that is widely distributed in many ti...
Sanguinarine (SA) has been used in toothpastes and oral rinse products and has been recently applied...
Inhibition of angiogenesis is an important new approach for cancer treatment and the research on thi...
Follicular growth is characterized by an augmented vascularization, possibly driven by a fall in the...