The interactions of 4-nitroquinoline-1-oxide (NQO) with the four 5{prime}-deoxyribonucleotides were probed using absorption spectra of the charge transfer bands and {sup 1}H and {sup 13}C NMR spectra of nucleotide-NQO mixtures. Applying a Benesi-Hildebrand type equation to the spectral data yielded equilibrium constants (K(dpG:NQO) = 16 M{sup -1} K(dpA:NQO) = 12 M{sup -1}, K(dpT:NQO) = K(dpC:NQO) = 4 M{sup -1}) which suggest the preference of NQO for the guanine residue in a DNA. From {sup 13}C and {sup 1}H NMR data, a structure for the dpG:NQO complex is proposed
High-resolution NMR techniques (proton and ^(19)F) have been used to study the interactions between ...
The molecular events in cells exposed to mutagenic and oncogenic quinoline N-oxides were examined by...
The reactivity of three hexacationic arene ruthenium metallaprisms towards isolated nucleotides and ...
Native calf thymus DNA and, to a lesser extent, poly dG: dC produced marked changes in the absorptio...
ABSTRACT: In the present article, the electronic structure of 4-nitroquinoline-1-oxide (4NQO) has be...
Optical titration studies, NMR studies and studies with DNA oligonucleotides have suggested that the...
We have studied the nuclear quadrupole interactions (NQI) of the 14N, 17O and 2H nuclei in the nucle...
We have studied the nuclear quadrupole interactions (NQI) of the (14)N, (17)O and (2)H nuclei in the...
Previous NMR and optical titration studies have suggested that the carcinogen 4- nitroquinoline-1-ox...
DNA secondary and tertiary structures are known to affect the reaction between the double helix and ...
The interaction between DNA and a benzothiazole-quinoline cyanine dye with a trimethine bridge (TO-P...
Background: G-quadruplexes have become important drug-design targets for the treatment of various hu...
The association of 5′,8-cyclo-2′-deoxyguanosine (cdG), a DNA tandem lesion, with its complementary b...
Noncovalent forces rule the interactions between biomolecules. Inspired by a biomolecular interactio...
Background G-quadruplexes have become important drug-design targets for the treatment of various hum...
High-resolution NMR techniques (proton and ^(19)F) have been used to study the interactions between ...
The molecular events in cells exposed to mutagenic and oncogenic quinoline N-oxides were examined by...
The reactivity of three hexacationic arene ruthenium metallaprisms towards isolated nucleotides and ...
Native calf thymus DNA and, to a lesser extent, poly dG: dC produced marked changes in the absorptio...
ABSTRACT: In the present article, the electronic structure of 4-nitroquinoline-1-oxide (4NQO) has be...
Optical titration studies, NMR studies and studies with DNA oligonucleotides have suggested that the...
We have studied the nuclear quadrupole interactions (NQI) of the 14N, 17O and 2H nuclei in the nucle...
We have studied the nuclear quadrupole interactions (NQI) of the (14)N, (17)O and (2)H nuclei in the...
Previous NMR and optical titration studies have suggested that the carcinogen 4- nitroquinoline-1-ox...
DNA secondary and tertiary structures are known to affect the reaction between the double helix and ...
The interaction between DNA and a benzothiazole-quinoline cyanine dye with a trimethine bridge (TO-P...
Background: G-quadruplexes have become important drug-design targets for the treatment of various hu...
The association of 5′,8-cyclo-2′-deoxyguanosine (cdG), a DNA tandem lesion, with its complementary b...
Noncovalent forces rule the interactions between biomolecules. Inspired by a biomolecular interactio...
Background G-quadruplexes have become important drug-design targets for the treatment of various hum...
High-resolution NMR techniques (proton and ^(19)F) have been used to study the interactions between ...
The molecular events in cells exposed to mutagenic and oncogenic quinoline N-oxides were examined by...
The reactivity of three hexacationic arene ruthenium metallaprisms towards isolated nucleotides and ...