Recently, we reported a convergent cyclopropanation–Cope approach to the core of ineleganolide, which was the first disclosed synthesis of the core of the norditerpene natural product ineleganolide. In this complementary work, a model system for the core of ineleganolide has been prepared through a series of tandem cyclopropanation–Cope and translactonization–Cope rearrangements. Work with this model system has enriched our understanding of the cyclopropanation–Cope rearrangement sequence. Additionally, research into this model system has driven the development of tandem translactonization–Cope rearrangements
The Cope rearrangement of gem-dimethyl-substituted divinylcyclopropanes has been used to construct f...
This thesis explores the development of the tandem oxy-Cope/ene rearrangement and its application to...
It was the purpose of this thesis work to develop new cyclization sequences to be used toward the sy...
Recently, we reported a convergent cyclopropanation–Cope approach to the core of ineleganolide, whic...
An enantioselective and diastereoselective approach toward the synthesis of the polycyclic norditerp...
Late-stage synthetic efforts to advance the enatio- and diastereoselectively constructed [6,7,5,5]-f...
Ineleganolide, horiolide, kavaranolide, sinulochmodin C, scabrolide A, scabrolide B, and yonarolide ...
The dissertation describes efforts to develop a chemical synthesis of the marine natural product ine...
This thesis describes the efforts of Professor James Leighton and myself toward the synthesis of the...
Described is the construction of the N-methylwelwitindolinone C core via an efficient strategy that ...
An enantioselective and diastereoselective approach toward the synthesis of the tetracyclic scaffold...
A new and flexible approach toward the synthesis of 6,12-guaianolide anticancer drugs such as trilob...
An enantioselective and diastereoselective approach toward the synthesis of the tetracyclic scaffold...
We thank EPSRC (UK) for a DTA studentship for C.A.J.The bioactive natural product perophoramidine ha...
A new Lewis acid-assisted Brønsted acid cascade approach for the stereoselective formation of the te...
The Cope rearrangement of gem-dimethyl-substituted divinylcyclopropanes has been used to construct f...
This thesis explores the development of the tandem oxy-Cope/ene rearrangement and its application to...
It was the purpose of this thesis work to develop new cyclization sequences to be used toward the sy...
Recently, we reported a convergent cyclopropanation–Cope approach to the core of ineleganolide, whic...
An enantioselective and diastereoselective approach toward the synthesis of the polycyclic norditerp...
Late-stage synthetic efforts to advance the enatio- and diastereoselectively constructed [6,7,5,5]-f...
Ineleganolide, horiolide, kavaranolide, sinulochmodin C, scabrolide A, scabrolide B, and yonarolide ...
The dissertation describes efforts to develop a chemical synthesis of the marine natural product ine...
This thesis describes the efforts of Professor James Leighton and myself toward the synthesis of the...
Described is the construction of the N-methylwelwitindolinone C core via an efficient strategy that ...
An enantioselective and diastereoselective approach toward the synthesis of the tetracyclic scaffold...
A new and flexible approach toward the synthesis of 6,12-guaianolide anticancer drugs such as trilob...
An enantioselective and diastereoselective approach toward the synthesis of the tetracyclic scaffold...
We thank EPSRC (UK) for a DTA studentship for C.A.J.The bioactive natural product perophoramidine ha...
A new Lewis acid-assisted Brønsted acid cascade approach for the stereoselective formation of the te...
The Cope rearrangement of gem-dimethyl-substituted divinylcyclopropanes has been used to construct f...
This thesis explores the development of the tandem oxy-Cope/ene rearrangement and its application to...
It was the purpose of this thesis work to develop new cyclization sequences to be used toward the sy...