This dissertation is concerned with testing economic growth theory using data from US States. Work on endogenous growth has recently been extended to determine the rate of technological change across economies where the incentive to innovate is linked to economic rewards. These models of endogenous innovation are on the cutting edge of theoretical advances in economic growth. I extend the endogenous innovation literature to study the consequences of knowledge spillovers and the different industrial concentrations that clearly exist across states. This extension of the theory suggests it is reasonable to expect rates of innovation to differ across states if knowledge spillovers across economies are not significant, even though states are sim...