Add to ORKGThe successful delivery of vaccine antigens such as peptides and proteins to stimulate CD4 and CD8 T cell immunity could provide a prevention or treatment of infectious diseases and malignant disorders. This project tested different strategies of peptide delivery to phagocytic cells using using Beta-glucan particles (GPs), and assayed the in vitro immune-stimulatory capabilities. GPs are hollow microparticles derived from Baker’s yeast that can be used to encapsulate or bind peptide payloads to ensure delivery to target cells. Various synthetic strategies were evaluated to identify an effective delivery method for in vitro testing using a T-cell proliferation assay
A brief overview of carbohydrate antigens processing and uptakes involved in the adaptive immune sys...
The tendency for the Human Immunodeficiency Virus (HIV) to proliferate and mutate it’s trimeric enve...
The Dopamine Transporter (DAT) is a trans-membrane protein that is part of the SLC6 gene family. Pro...
Human Cytomegalovirus (HCMV) infection can progress into a persistent and life-threatening disease i...
In response to a viral antigen, the immune system produces epitope-specific T-cells. The majority be...
Diaminopimelic acid (DAP) is a modified lysine amino acid required for cell wall synthesis in most b...
This project focused on investigating the binding properties of a panel of rabbit monoclonal antibod...
The purpose of this project was to determine whether the Coxsackievirus B (CVB) uses toll-like recep...
The goal of this project was to document and evaluate the technology of cancer vaccines, to determin...
Activated CD4+ T-cells targeting specific auto-antigenic peptides of myelin proteins mediate the pat...
This project explores the function of Core Binding Factor (CBF) in B-cell development, and its regul...
Medulloblastoma (MB) patients suffer a poor prognosis and limitations of current treatments necessit...
The goal of this project was to test Pichinde virus isolates for in vitro and in vivo viability, and...
Influenza is a major cause of human illness and death, and as such requires vast attention.Current v...
Eukaryotic vesicle targeting and fusion are conserved processes that involve SNARE and SM proteins. ...
A brief overview of carbohydrate antigens processing and uptakes involved in the adaptive immune sys...
The tendency for the Human Immunodeficiency Virus (HIV) to proliferate and mutate it’s trimeric enve...
The Dopamine Transporter (DAT) is a trans-membrane protein that is part of the SLC6 gene family. Pro...
Human Cytomegalovirus (HCMV) infection can progress into a persistent and life-threatening disease i...
In response to a viral antigen, the immune system produces epitope-specific T-cells. The majority be...
Diaminopimelic acid (DAP) is a modified lysine amino acid required for cell wall synthesis in most b...
This project focused on investigating the binding properties of a panel of rabbit monoclonal antibod...
The purpose of this project was to determine whether the Coxsackievirus B (CVB) uses toll-like recep...
The goal of this project was to document and evaluate the technology of cancer vaccines, to determin...
Activated CD4+ T-cells targeting specific auto-antigenic peptides of myelin proteins mediate the pat...
This project explores the function of Core Binding Factor (CBF) in B-cell development, and its regul...
Medulloblastoma (MB) patients suffer a poor prognosis and limitations of current treatments necessit...
The goal of this project was to test Pichinde virus isolates for in vitro and in vivo viability, and...
Influenza is a major cause of human illness and death, and as such requires vast attention.Current v...
Eukaryotic vesicle targeting and fusion are conserved processes that involve SNARE and SM proteins. ...
A brief overview of carbohydrate antigens processing and uptakes involved in the adaptive immune sys...
The tendency for the Human Immunodeficiency Virus (HIV) to proliferate and mutate it’s trimeric enve...
The Dopamine Transporter (DAT) is a trans-membrane protein that is part of the SLC6 gene family. Pro...