In this issue of , Nakajima et al. (https://doi.org/10.1084/jem.20180427) demonstrate that glycan-dependent, epitope-independent IgA coating of intestinal bacteria alters bacterial gene expression and metabolism. This conferred coated bacteria with fitness within the mucus niche and contributed to intestinal homeostasis through cross-phylum interactions
Immunoglobulin A (IgA) is prominently secreted at mucosal surfaces and coats a fraction of the intes...
Immunology research in the last 50 years has made huge progress in understanding the mechanisms of a...
Dimeric IgA secreted across mucous membranes in response to nonpathogenic taxa of the microbiota acc...
IgA is induced through T-cell-dependent and -independent pathways. In this issue, Bunker et al. (201...
Antibodies of the secretory IgA (SIgA) class comprise the first line of antigen-specific immune defe...
International audienceIn humans, several grams of IgA are secreted every day in the intestinal lumen...
Intestinal bacteria outnumber our own human cells in conditions of both health and disease. It has l...
Antibodies of the secretory IgA (SIgA) class comprise the first line of antigen-specific immune defe...
Secretory IgA has long been a divisive molecule. Some immunologists point to the mild phenotype of I...
Humans live in symbiosis with 10(14) commensal bacteria among which >99% resides in their gastroi...
In humans, several grams of IgA are secreted every day in the intestinal lumen. While only one IgA i...
Secretory IgA (SIgA) serves as the first line of defense in protecting the intestinal epithelium fro...
Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. I...
Secretory IgA (SIgA) plays an important role in the protection and homeostatic regulation of intesti...
Intestinal bacteria outnumber our own human cells in conditions of both health and disease. It has l...
Immunoglobulin A (IgA) is prominently secreted at mucosal surfaces and coats a fraction of the intes...
Immunology research in the last 50 years has made huge progress in understanding the mechanisms of a...
Dimeric IgA secreted across mucous membranes in response to nonpathogenic taxa of the microbiota acc...
IgA is induced through T-cell-dependent and -independent pathways. In this issue, Bunker et al. (201...
Antibodies of the secretory IgA (SIgA) class comprise the first line of antigen-specific immune defe...
International audienceIn humans, several grams of IgA are secreted every day in the intestinal lumen...
Intestinal bacteria outnumber our own human cells in conditions of both health and disease. It has l...
Antibodies of the secretory IgA (SIgA) class comprise the first line of antigen-specific immune defe...
Secretory IgA has long been a divisive molecule. Some immunologists point to the mild phenotype of I...
Humans live in symbiosis with 10(14) commensal bacteria among which >99% resides in their gastroi...
In humans, several grams of IgA are secreted every day in the intestinal lumen. While only one IgA i...
Secretory IgA (SIgA) serves as the first line of defense in protecting the intestinal epithelium fro...
Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. I...
Secretory IgA (SIgA) plays an important role in the protection and homeostatic regulation of intesti...
Intestinal bacteria outnumber our own human cells in conditions of both health and disease. It has l...
Immunoglobulin A (IgA) is prominently secreted at mucosal surfaces and coats a fraction of the intes...
Immunology research in the last 50 years has made huge progress in understanding the mechanisms of a...
Dimeric IgA secreted across mucous membranes in response to nonpathogenic taxa of the microbiota acc...
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