IgA is induced through T-cell-dependent and -independent pathways. In this issue, Bunker et al. (2015) now show that the T-cell-independent pathway is sufficient to coat most small intestinal microbes specifically, and Fransen et al. (2015) find that IgA coating promotes uptake of microbes into Peyer’s patches and drives further induction in a positive-feedback loop
Recent studies demonstrate that immunoglobulin A (IgA) is critical for limiting chronic inflammation...
Production of IgA at mucosal surfaces is one of the most striking features of the mucosal immune sys...
IgA is the most abundant immunoglobulin produced in mammals, and is mostly secreted across mucous me...
IgA is induced through T-cell-dependent and -independent pathways. In this issue, Bunker et al. (201...
IgA is induced through T-cell-dependent and -independent pathways. In this issue, Bunker et al. (201...
In this issue of , Nakajima et al. (https://doi.org/10.1084/jem.20180427) demonstrate that glycan-de...
Secretory IgA has long been a divisive molecule. Some immunologists point to the mild phenotype of I...
Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. I...
SummaryImmunoglobulin A (IgA) is prominently secreted at mucosal surfaces and coats a fraction of th...
IgA antibodies help maintain intestinal immune homeostasis with resident commensal species; however,...
SummaryBacteria colonize the intestine shortly after birth and thereafter exert several beneficial f...
Immunoglobulin A (IgA) is prominently secreted at mucosal surfaces and coats a fraction of the intes...
In humans and mice, mucosal immune responses are dominated by IgA antibodies and the cytokine TGF-β,...
Intestinal bacteria outnumber our own human cells in conditions of both health and disease. It has l...
International audienceBACKGROUND: Commensals induce local IgA responses essential to the induction o...
Recent studies demonstrate that immunoglobulin A (IgA) is critical for limiting chronic inflammation...
Production of IgA at mucosal surfaces is one of the most striking features of the mucosal immune sys...
IgA is the most abundant immunoglobulin produced in mammals, and is mostly secreted across mucous me...
IgA is induced through T-cell-dependent and -independent pathways. In this issue, Bunker et al. (201...
IgA is induced through T-cell-dependent and -independent pathways. In this issue, Bunker et al. (201...
In this issue of , Nakajima et al. (https://doi.org/10.1084/jem.20180427) demonstrate that glycan-de...
Secretory IgA has long been a divisive molecule. Some immunologists point to the mild phenotype of I...
Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. I...
SummaryImmunoglobulin A (IgA) is prominently secreted at mucosal surfaces and coats a fraction of th...
IgA antibodies help maintain intestinal immune homeostasis with resident commensal species; however,...
SummaryBacteria colonize the intestine shortly after birth and thereafter exert several beneficial f...
Immunoglobulin A (IgA) is prominently secreted at mucosal surfaces and coats a fraction of the intes...
In humans and mice, mucosal immune responses are dominated by IgA antibodies and the cytokine TGF-β,...
Intestinal bacteria outnumber our own human cells in conditions of both health and disease. It has l...
International audienceBACKGROUND: Commensals induce local IgA responses essential to the induction o...
Recent studies demonstrate that immunoglobulin A (IgA) is critical for limiting chronic inflammation...
Production of IgA at mucosal surfaces is one of the most striking features of the mucosal immune sys...
IgA is the most abundant immunoglobulin produced in mammals, and is mostly secreted across mucous me...
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