Recognition of foreign DNA in intracellular compartments or in the cytoplasm sounds an alarm bell signaling pathogenic invasion. In response, innate immune DNA-sensing pathways launch an antimicrobial type I interferon (IFN) response, which becomes damaging to the host if unregulated or inappropriately activated by self-DNA. This Select highlights recent insights into activation and regulation of innate immune DNA-sensing pathways
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
Recognition of foreign DNA in intracellular compartments or in the cytoplasm sounds an alarm bell si...
Although it has been appreciated for some years that cytosolic DNA is immune stimulatory, it is only...
Detection of pathogen-derived nucleic acids by pattern recognition receptors (PRRs) is essential for...
<p>(A) Cytosolic DNA from invading viruses and bacteria engage and activate AIM2 binding to the adap...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
Although it has been appreciated for some years that cytosolic DNA is immune stimulatory, it is only...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
Recognition of foreign DNA in intracellular compartments or in the cytoplasm sounds an alarm bell si...
Although it has been appreciated for some years that cytosolic DNA is immune stimulatory, it is only...
Detection of pathogen-derived nucleic acids by pattern recognition receptors (PRRs) is essential for...
<p>(A) Cytosolic DNA from invading viruses and bacteria engage and activate AIM2 binding to the adap...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
Although it has been appreciated for some years that cytosolic DNA is immune stimulatory, it is only...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...
The detection of intracellular DNA has emerged to be a key event in the innate immune response to vi...