An increasing impact of micromechanically governed uncertainties is nowadays foreseen due to the trend of progressively reducing the footprint of MEMS (Microelectromechanical Systems) devices. For polysilicon MEMS, the two major sources of uncertainties, as resulting from the microfabrication process, are linked to the polycrystalline morphology and to the etching. In this review, we summarize some of our recent results related to the statistical assessment of the aforementioned sources, on the basis of experimental data acquired via an on-chip testing device specifically designed to enhance such effects. Through standard electrostatic actuation and readout, the scattering in the response of a series of nominally identical cantilever struct...