Change in the arachidonic acid metabolism pathway (KEGG map ID: mmu00590) based on the differentially expressed genes in bronchial smooth muscle tissues of the antigen-challenged mice.

Total RNA sample of each mouse (4 animals, respectively) was subjected to the microarray analysis, and Kyoto Encyclopedia of Genes and Genomes pathway analysis of differentially expressed genes was performed. Enzymatic reactions are marked by arrows. Fold change values of differentially expressed genes are shown in colors. Different colors in a box for the same module indicate various genes with differing expression. White boxes of pathway map indicate modules that are not relevant to the mouse. Green color boxes of pathway map indicate modules that are not mapped (the gene is in the pathway map but its expression was not shown in the present study). The pathway modules containing differentially expressed genes with statistical significance are marked with red stars.