A database of simulated tumor genomes towards accurate detection of somatic small variants in cancer - Fig 3

The fraction of 64 trinucleotide contexts for successful somatic SNV sites (left panel) and unsuccessful ones (right panel). Three bases (from -1 bp to +1 bp) centered on the simulated somatic sites of hg38 reference genome were extracted for successful and unsuccessful somatic SNV spike-ins respectively. Then we calculated the proportion by dividing the number of somatic SNVs with a type of trinucleotide context by the total number.