<p>(A) Number of SNVs and indels. (B) Total number of somatic nucleotide base changes. (C) Ts to Tv ratio of each tumor. SNV: single nucleotide variation; indel: insertion/deletion; Ts: transition; Tv: transversion.</p
Results of somatic SNV analysis on subset of human breast and ovarian tumour samples [7]. Subtrees w...
<p>(A) Somatic mutation spectrum in adenoma and adenocarcinoma, similar with 11 colorectal cancers p...
<p>Allelic ratio for allele-specific copy number gain (A) and loss (B) events at heterozygous SNP lo...
On average, we identified 220 (range, 126–358) somatically acquired point mutations per case. Of the...
The fraction of 64 trinucleotide contexts for successful somatic SNV sites (left panel) and unsucces...
Somatic single nucleotide variants (SNVs) are mutations resulting from the substitution of a single ...
International audienceSingle-nucleotide variants (SNVs) are the most frequent genetic changes found ...
<p>Proportion of somatic SNVs by class (C->A, C->G, C->T, T->A, T->C and T-G) in the primary, metast...
Only coding non-silent somatic mutations are considered. (A) Mutation rates (top panel), top mutated...
<p>On the left the three peaks represent kernel distribution density plots of the frequencies of som...
<p>(Coefficient of determination (R<sup>2</sup>) >0.99 for all fitted curves).</p
Much of our current understanding of cancer has come from investigating how normal cells are transfo...
<p>Summary of the number and types of somatic variants detected by tumor/normal genome-wide exome an...
Precision medicine attempts to individualize cancer therapy by matching tumor-specific genetic chang...
<p>The overall concordance of somatic SNV calls between FFPE-frozen paired samples. A. The overlappi...
Results of somatic SNV analysis on subset of human breast and ovarian tumour samples [7]. Subtrees w...
<p>(A) Somatic mutation spectrum in adenoma and adenocarcinoma, similar with 11 colorectal cancers p...
<p>Allelic ratio for allele-specific copy number gain (A) and loss (B) events at heterozygous SNP lo...
On average, we identified 220 (range, 126–358) somatically acquired point mutations per case. Of the...
The fraction of 64 trinucleotide contexts for successful somatic SNV sites (left panel) and unsucces...
Somatic single nucleotide variants (SNVs) are mutations resulting from the substitution of a single ...
International audienceSingle-nucleotide variants (SNVs) are the most frequent genetic changes found ...
<p>Proportion of somatic SNVs by class (C->A, C->G, C->T, T->A, T->C and T-G) in the primary, metast...
Only coding non-silent somatic mutations are considered. (A) Mutation rates (top panel), top mutated...
<p>On the left the three peaks represent kernel distribution density plots of the frequencies of som...
<p>(Coefficient of determination (R<sup>2</sup>) >0.99 for all fitted curves).</p
Much of our current understanding of cancer has come from investigating how normal cells are transfo...
<p>Summary of the number and types of somatic variants detected by tumor/normal genome-wide exome an...
Precision medicine attempts to individualize cancer therapy by matching tumor-specific genetic chang...
<p>The overall concordance of somatic SNV calls between FFPE-frozen paired samples. A. The overlappi...
Results of somatic SNV analysis on subset of human breast and ovarian tumour samples [7]. Subtrees w...
<p>(A) Somatic mutation spectrum in adenoma and adenocarcinoma, similar with 11 colorectal cancers p...
<p>Allelic ratio for allele-specific copy number gain (A) and loss (B) events at heterozygous SNP lo...