Figure S2. Focus on the 1H-NMR regions IR89, IR90 and IR91. The β-CH2 protons of glutamate are diastereotopic since they are located on a carbon atom next to an asymmetric carbon atom. This results in a complex multiplet of several peaks situated between 2.03 and 2.22 ppm, and appearing in the following three integration regions: IR89 = glutamate and methionine; IR90 = glutamate, glutamine, proline and methionine; and IR91 = CH2-C=O or CH2-CH=CH- of fatty acids, glutamate, isoleucine, methionine and proline. A: 1H-NMR spectrum of a lung cancer patient. B:: 1H-NMR spectrum of a patient with lung inflammation. (PDF 512 kb
Details MR sequences. Details blood sample measurements. Table S1. Patient details. Figure S1. Trans...
Figure S1. Nuclear DNA content and mitochondrial DNA content do not differ by clinical group. Nuclea...
PCA and OPLS-DA scores plots based on 1H NMR spectrum data of serum samples obtained from two gout s...
Figure S3. Spiking experiments glutamate and methionine. These experiments demonstrate that the prot...
Figure S1. Volcano plot presenting an overview of the most meaningful differences between the metabo...
Elaborate explanation of the Leave-One-Out-Cross-Validation (COOCV) method and evaluation of the cla...
Figure showing HR MAS MRS data from untreated MAS98.06 and MAS98.12 tumors. a) Average 13C HR MAS MR...
Table S1. Performance (mean) of the PLS-LDA classification for different top K signature sizes, full...
Table S1. Potential serum biomarkers identified by 1H NMR and their means and standard deviation val...
Abstract Background Pulmonary imaging often identifies suspicious abnormalities resulting in supplem...
Contains fulltext : 50036.pdf (publisher's version ) (Closed access)A diagnosis of...
Additional file 4: Fig. S4 Comparison of clean vs. blood-contaminated CSF NMR spectra. (A) 1D-NOESY-...
Figure S2. Extracellular 2-HG levels after 13C-substrate labellings detected by LC-MS in U251 IDH1m ...
ß-Lap mechanism and GOT2 to GLUD1 Kaplan–Meier curve. (A) ß-lap mechanism of action. In the cytosol ...
Glutamate metabolism pathway metabolite member normalized concentrations from pathway analysis by gl...
Details MR sequences. Details blood sample measurements. Table S1. Patient details. Figure S1. Trans...
Figure S1. Nuclear DNA content and mitochondrial DNA content do not differ by clinical group. Nuclea...
PCA and OPLS-DA scores plots based on 1H NMR spectrum data of serum samples obtained from two gout s...
Figure S3. Spiking experiments glutamate and methionine. These experiments demonstrate that the prot...
Figure S1. Volcano plot presenting an overview of the most meaningful differences between the metabo...
Elaborate explanation of the Leave-One-Out-Cross-Validation (COOCV) method and evaluation of the cla...
Figure showing HR MAS MRS data from untreated MAS98.06 and MAS98.12 tumors. a) Average 13C HR MAS MR...
Table S1. Performance (mean) of the PLS-LDA classification for different top K signature sizes, full...
Table S1. Potential serum biomarkers identified by 1H NMR and their means and standard deviation val...
Abstract Background Pulmonary imaging often identifies suspicious abnormalities resulting in supplem...
Contains fulltext : 50036.pdf (publisher's version ) (Closed access)A diagnosis of...
Additional file 4: Fig. S4 Comparison of clean vs. blood-contaminated CSF NMR spectra. (A) 1D-NOESY-...
Figure S2. Extracellular 2-HG levels after 13C-substrate labellings detected by LC-MS in U251 IDH1m ...
ß-Lap mechanism and GOT2 to GLUD1 Kaplan–Meier curve. (A) ß-lap mechanism of action. In the cytosol ...
Glutamate metabolism pathway metabolite member normalized concentrations from pathway analysis by gl...
Details MR sequences. Details blood sample measurements. Table S1. Patient details. Figure S1. Trans...
Figure S1. Nuclear DNA content and mitochondrial DNA content do not differ by clinical group. Nuclea...
PCA and OPLS-DA scores plots based on 1H NMR spectrum data of serum samples obtained from two gout s...