Red = control group, blue = vaccinated group. Green dashed line = antibody threshold that gives greatest level of protection. STD, HIGH, LOW: see Table 1 for definitions.</p
<p>Groups of BALB/c mice (n = 10) were vaccinated once (graphs on left) or twice (graphs on right) w...
The left hand plot displays the probability of successful (immunity-boosting) exposure for a simulat...
<p>A: The serum IgG trough level is maintained by substitution therapy with treatment frequency an...
Light blue dots = trials of size 20,000; dark green dots = trials of size 60,000; Blue dotted line =...
Parameters for simulations of antibody distributions in vaccinated and control populations for three...
Light blue dots = trials of size 20,000; dark green dots = trials of size 60,000; Blue dotted line =...
Light blue dots = trials of size 20,000; dark green dots = trials of size 60,000; Blue dotted line =...
A: Step function with antibody levels higher than the 1 mcg/mL threshold produced sterilizing immuni...
In the development of new vaccines, understanding the level of vaccine-induced antibody that is suff...
In the development of new vaccines, understanding the level of vaccine-induced antibody that is suff...
<p>Dashed lines represent the median number of cases in simulations with vaccination, and the solid ...
(A) Histograms representing the frequency an amino acid at each position in the RBD escapes vaccine ...
<p>Each plot shows the median (diamonds) and 95% predictive interval for the proportion of cases ave...
Bars display point estimates and 95% confidence intervals obtained from fitting generalized additive...
For many vaccines the amount of antibodies induced has a positive correlation with the likelihood of...
<p>Groups of BALB/c mice (n = 10) were vaccinated once (graphs on left) or twice (graphs on right) w...
The left hand plot displays the probability of successful (immunity-boosting) exposure for a simulat...
<p>A: The serum IgG trough level is maintained by substitution therapy with treatment frequency an...
Light blue dots = trials of size 20,000; dark green dots = trials of size 60,000; Blue dotted line =...
Parameters for simulations of antibody distributions in vaccinated and control populations for three...
Light blue dots = trials of size 20,000; dark green dots = trials of size 60,000; Blue dotted line =...
Light blue dots = trials of size 20,000; dark green dots = trials of size 60,000; Blue dotted line =...
A: Step function with antibody levels higher than the 1 mcg/mL threshold produced sterilizing immuni...
In the development of new vaccines, understanding the level of vaccine-induced antibody that is suff...
In the development of new vaccines, understanding the level of vaccine-induced antibody that is suff...
<p>Dashed lines represent the median number of cases in simulations with vaccination, and the solid ...
(A) Histograms representing the frequency an amino acid at each position in the RBD escapes vaccine ...
<p>Each plot shows the median (diamonds) and 95% predictive interval for the proportion of cases ave...
Bars display point estimates and 95% confidence intervals obtained from fitting generalized additive...
For many vaccines the amount of antibodies induced has a positive correlation with the likelihood of...
<p>Groups of BALB/c mice (n = 10) were vaccinated once (graphs on left) or twice (graphs on right) w...
The left hand plot displays the probability of successful (immunity-boosting) exposure for a simulat...
<p>A: The serum IgG trough level is maintained by substitution therapy with treatment frequency an...