Effect of Dox on intracellular NAD+ levels in RWPE1 and LNCaP cells. (a, b) Intracellular NAD+ levels were measured relative to DNA measurements (a) or total cellular protein (b) in naĂŻve RWPE1 (a) and LNCaP (b) cells exposed to varying concentrations of Dox. Results are presented relative to no Dox control. Plot shows mean of 4 replicates per time point ÂąSEM. Newman-Keuls Multiple Comparison Test. (TIF 67 kb
Boxplots of CpGs in the top diagnostic model from hypermethylated CpGs. Normal data is from benign-a...
Quantitative analysis of Fig. 4a (A) and C (B). Data are expressed as mean ± SEM of the positive cel...
Table S1. Results of modeling using continuous and binary methylation levels. Table S2. the range of...
Effect of extracellular NAD+ on intracellular NAD+ and NADH levels. (a, b) After the addition of exo...
NAMPT inhibitor FK866 depletes NAD+ levels and impairs proliferation. (a, b, d, e, g, h) Intracellul...
Effect of CD38 expression on RWPE1, LNCaP and DU145 cell proliferation. (a) RWPE1 cell proliferation...
Effect of CD38 on expression of enzymes involved in NAD+ metabolism. (a, b) Western blots show expre...
NAD+ and NADH levels in wild-type and CD38 knockout mouse tissues. NAD+ and NADH levels were measure...
Re-expression of CD38 in prostate cancer cell lines after treatment with DNA methyltransferase inhib...
CpG hypermethylation of CD38 in prostate cancer cell lines. Related to Fig. 3, methylation heat maps...
In silico analysis of TCGA data correlating DNA methylation and mRNA expression of commonly methylat...
Figure S3. a SW837 cells were treated either with DMSO or the DOT1L inhibitor EPZ5676 (1 μM) for eit...
Table S1. Primer sequences for β-Actin, miR-34b/c, and miR-193b (panel #1). Table S2. Scorpion prime...
Figure S4. A. qRT-PCR results for mRNA levels of actin, AMPK, PDH E2, PDH E3bp and PDH E1α from MCF7...
Figure S2. A. Fold changes of cell number was measured and plotted for shCon and shTPD54 stable cell...
Boxplots of CpGs in the top diagnostic model from hypermethylated CpGs. Normal data is from benign-a...
Quantitative analysis of Fig. 4a (A) and C (B). Data are expressed as mean ± SEM of the positive cel...
Table S1. Results of modeling using continuous and binary methylation levels. Table S2. the range of...
Effect of extracellular NAD+ on intracellular NAD+ and NADH levels. (a, b) After the addition of exo...
NAMPT inhibitor FK866 depletes NAD+ levels and impairs proliferation. (a, b, d, e, g, h) Intracellul...
Effect of CD38 expression on RWPE1, LNCaP and DU145 cell proliferation. (a) RWPE1 cell proliferation...
Effect of CD38 on expression of enzymes involved in NAD+ metabolism. (a, b) Western blots show expre...
NAD+ and NADH levels in wild-type and CD38 knockout mouse tissues. NAD+ and NADH levels were measure...
Re-expression of CD38 in prostate cancer cell lines after treatment with DNA methyltransferase inhib...
CpG hypermethylation of CD38 in prostate cancer cell lines. Related to Fig. 3, methylation heat maps...
In silico analysis of TCGA data correlating DNA methylation and mRNA expression of commonly methylat...
Figure S3. a SW837 cells were treated either with DMSO or the DOT1L inhibitor EPZ5676 (1 μM) for eit...
Table S1. Primer sequences for β-Actin, miR-34b/c, and miR-193b (panel #1). Table S2. Scorpion prime...
Figure S4. A. qRT-PCR results for mRNA levels of actin, AMPK, PDH E2, PDH E3bp and PDH E1α from MCF7...
Figure S2. A. Fold changes of cell number was measured and plotted for shCon and shTPD54 stable cell...
Boxplots of CpGs in the top diagnostic model from hypermethylated CpGs. Normal data is from benign-a...
Quantitative analysis of Fig. 4a (A) and C (B). Data are expressed as mean ± SEM of the positive cel...
Table S1. Results of modeling using continuous and binary methylation levels. Table S2. the range of...