Additional file 1: of Clinical exome sequencing for fetuses with ultrasound abnormalities and a suspected Mendelian disorder

Figure S1. Comparison of proband versus trio exome workflows. Figure S2. Fetal sample types received and culturing time prior to prenatal exome sequencing. Figure S3. Referring practices. Table S1. Quality metrics of exome sequencing data of the fetal and parental samples. Table S2. Excluded samples without a final report. Table S3. Incidental findings reported for prenatal exome tests. Table S4. Reported fetal phenotypes. Table S5. Pairwise statistical analysis of diagnostic rate based on number of affected organ systems, corrected for multiple comparisons. Table S6. Regions of absence of heterozygosity (AOH) in cases with homozygous variants underlying the molecular diagnosis. Table S7. Pregnancy outcomes for locally referred cases. (PDF 8142 kb