Additional file 1: of Whole exome sequencing (WES) on formalin-fixed, paraffin-embedded (FFPE) tumor tissue in gastrointestinal stromal tumors (GIST)

Table S1. Clinical and biological data of the patients included in the study. Table S2. Tagmented DNA library and post-enrichment pooled library yield and average size. Table S3. Lane-specific sequencing quality parameters (cluster density, percentage of clusters passing filter, total number or reads passing filter and percentage of bases with quality ≥ Q30). Table S4. Sample-specific sequencing quality scores (percentage of bases with quality ≥ Q30 and average Q-score). Table S5. List of somatic somatic disease-related mutations (non-synonimous and nonsense SNVs and InDels located in the coding region and splicing sites). Variants are flagged as shared if present both in FF and FFPE samples, FP if called only in FFPE and FN if called only in FF. Ref: reference; Alt: alternative; Cov: Coverage. Figure S1. Tagmented DNA library size distribution as analyzed by Agilent DNA 1000 kit. Figure S2. Average insert size of the exome libraries sequenced at 100bp x 2. Figure S3. Percentage of reads mapping on-target and off-target, i.e., outside the 37Mb Nextera target region used for exome enrichment. (DOCX 100 kb