The average measured mutation frequency across all five mutations is plotted against the average expected frequency, for two replicates. Error bars indicate the standard error of the mean at each point, while the dashed line indicates 1:1 concordance between expected and measured values. Data is shown in S3 Table.</p
<p>Average frequency (five replicates) of the resistant allele compared to the erroneous alleles at ...
<p>The averaged concordance values (the bars) and the corresponding standard deviations (the error b...
<p>Frequency of fixation when introduced into nondifferentiating populations (filled circles), stem ...
The error rate was calculated per run as the count of all non-reference calls per mutation type over...
Relative mutational frequency compares the frequency of resistance mutations against phage pairs to ...
<p>(A) Shown are the expected and observed mean sample frequencies of disease mutations for four dif...
<p>Data are represented as a column graph depicting scores mean value for (A) homozygous and (B) het...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
<p>The expected frequency of mutants according to geometric distribution is shown in bold italics.</...
<p>Significant differences between rates in young singletons as compares to the other two datasets a...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
<p>Dark grey are populations evolved in the benign environment and light grey are the populations ev...
<p>a, Relationship between the average and variance of the substitution error presented as the numbe...
<p>The frequency of KRAS, BRAF and PIK3CA mutations according to different patterns.</p
<p>Error bars are 95% confidence intervals (CI) for the observed phenotypic variation. Statistical d...
<p>Average frequency (five replicates) of the resistant allele compared to the erroneous alleles at ...
<p>The averaged concordance values (the bars) and the corresponding standard deviations (the error b...
<p>Frequency of fixation when introduced into nondifferentiating populations (filled circles), stem ...
The error rate was calculated per run as the count of all non-reference calls per mutation type over...
Relative mutational frequency compares the frequency of resistance mutations against phage pairs to ...
<p>(A) Shown are the expected and observed mean sample frequencies of disease mutations for four dif...
<p>Data are represented as a column graph depicting scores mean value for (A) homozygous and (B) het...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
<p>The expected frequency of mutants according to geometric distribution is shown in bold italics.</...
<p>Significant differences between rates in young singletons as compares to the other two datasets a...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
<p>Dark grey are populations evolved in the benign environment and light grey are the populations ev...
<p>a, Relationship between the average and variance of the substitution error presented as the numbe...
<p>The frequency of KRAS, BRAF and PIK3CA mutations according to different patterns.</p
<p>Error bars are 95% confidence intervals (CI) for the observed phenotypic variation. Statistical d...
<p>Average frequency (five replicates) of the resistant allele compared to the erroneous alleles at ...
<p>The averaged concordance values (the bars) and the corresponding standard deviations (the error b...
<p>Frequency of fixation when introduced into nondifferentiating populations (filled circles), stem ...