(A) Spot assay of mutants before ASN2 knockout (ASN1WT-GFP ASN2 WT, ASN1D330V-GFP ASN2 WT, ASN1R354E-GFP ASN2 WT and ASN1E48K-GFP ASN2 WT). (B) Spot assay of mutants after ASN2 knockout (ASN1WT-GFP ASN2 KO, ASN1D330V-GFP ASN2 KO, ASN1R354E-GFP ASN2 KO and ASN1E48K-GFP ASN2 KO). (C) FACS analysis of ASN1WT-GFP ASN2 KO cells and ASN1D330V-GFP ASN2 KO cells.</p
<p>(A) Histone H2A and Rad53 phosphorylation induction by As(III) in G1 cells in the absence of Yku7...
<p>A) GFP-proEtx (1), GFP-proEtx-I51C/A114C (3), GFP-proEtx-V56C/A118C (5) and GFP-proEtx-H106P (7) ...
Cisplatin sensitivity is independent of germline development ability and insulin secretion ability b...
(A-D) Morphology of Asn1WT, Asn1E48K, Asn1R354E and Asn1D330V cytoophidium in ASN2 knockout backgrou...
(A) The proportion of cells with Asn1 cytoophidia in different dimer interface mutants. **PWT-GFP AS...
<p><i>(A) A FLCN phosphomimetic mutant (S62/73E) results in more rapid progression through the cell ...
(A) Representative confocal images of asna-1(+), and asna-1(A63V) 1-day-old adult animals co-express...
<p>A. Rad53 activation is impaired in <i>asf1Δ snf2Δ</i> double mutants. Cells were grown in the pre...
(A) Analysis of cisplatin sensitivity phenotype of seven million mutation project strains bearing po...
(A) Confocal images of cytoophidium in A1G, A2G, A1G A2KO, A2G A1KO cells. Scale bar, 2 μm. (B) Quan...
<p>(A) Expression of exogenous FLCN in UOK257 cells infected with retroviruses harboring empty vecto...
<p>(A) Position of eight <i>himar1</i> transposon (Tn) insertions (yellow arrowheads) that ameliorat...
<p>A. Western blot analysis shows p62 accumulation in Atg8a and Atg7 mutant heads and in Atg8a mutan...
<p>(<b>A</b>) The effect of the exogenous ASN and GSK-3β inhibitor, SB-216763, on PC12 cells viabili...
<p>Detection of cell apoptosis by Annexin V-PE/7-AAD staining. A-C: Annexin V-PE was read in FL2 and...
<p>(A) Histone H2A and Rad53 phosphorylation induction by As(III) in G1 cells in the absence of Yku7...
<p>A) GFP-proEtx (1), GFP-proEtx-I51C/A114C (3), GFP-proEtx-V56C/A118C (5) and GFP-proEtx-H106P (7) ...
Cisplatin sensitivity is independent of germline development ability and insulin secretion ability b...
(A-D) Morphology of Asn1WT, Asn1E48K, Asn1R354E and Asn1D330V cytoophidium in ASN2 knockout backgrou...
(A) The proportion of cells with Asn1 cytoophidia in different dimer interface mutants. **PWT-GFP AS...
<p><i>(A) A FLCN phosphomimetic mutant (S62/73E) results in more rapid progression through the cell ...
(A) Representative confocal images of asna-1(+), and asna-1(A63V) 1-day-old adult animals co-express...
<p>A. Rad53 activation is impaired in <i>asf1Δ snf2Δ</i> double mutants. Cells were grown in the pre...
(A) Analysis of cisplatin sensitivity phenotype of seven million mutation project strains bearing po...
(A) Confocal images of cytoophidium in A1G, A2G, A1G A2KO, A2G A1KO cells. Scale bar, 2 μm. (B) Quan...
<p>(A) Expression of exogenous FLCN in UOK257 cells infected with retroviruses harboring empty vecto...
<p>(A) Position of eight <i>himar1</i> transposon (Tn) insertions (yellow arrowheads) that ameliorat...
<p>A. Western blot analysis shows p62 accumulation in Atg8a and Atg7 mutant heads and in Atg8a mutan...
<p>(<b>A</b>) The effect of the exogenous ASN and GSK-3β inhibitor, SB-216763, on PC12 cells viabili...
<p>Detection of cell apoptosis by Annexin V-PE/7-AAD staining. A-C: Annexin V-PE was read in FL2 and...
<p>(A) Histone H2A and Rad53 phosphorylation induction by As(III) in G1 cells in the absence of Yku7...
<p>A) GFP-proEtx (1), GFP-proEtx-I51C/A114C (3), GFP-proEtx-V56C/A118C (5) and GFP-proEtx-H106P (7) ...
Cisplatin sensitivity is independent of germline development ability and insulin secretion ability b...