Gene Ontology terms enrichment analysis of differentially expressed genes detected by RNA-seq in schistosomula treated with GSK343.

Enriched GO terms for differentially expressed genes in schistosomula, separated by downregulated genes (A) and upregulated genes (B). The three major GO term categories, namely Biological Process, Cellular Component and Molecular Function are separately represented in each panel. The size of the circles is proportional to the number of genes in each significantly enriched category, as indicated at the lower part scales; the colors show the statistical significance of the enrichment, as indicated by the -log10 FDR values that appear in the color-coded scales at the bottom. A GO enrichment significance cutoff of FDR ≤ 0.05 was used.