Proportion of thoracic lymph nodes infected with Mtb in cynomolgus and rhesus macaques at necropsy.

A. Percent of thoracic LNs that were CFU+ (red) or CFU- (blue) at necropsy. Rhesus macaques had higher proportion of Mtb-infected lymph nodes than cynomolgus macaques. B. Proportion of lymph nodes that were uninfected (CFU-/CEQ-, light blue), infected but were sterile (CEQ+/CFU-, purple), had culturable Mtb but no detected genome (CFU+/CEQ-, yellow) and with culturable Mtb and Mtb genome (CFU+/CEQ+, pink). Threshold for detection of CEQ is 1000 genomes/LN. CFU limit of detection is 20/LN. Number of macaques and lymph nodes at each time point is in Table 1.