Additional file 1: of proBDNF is modified by advanced glycation end products in Alzheimer’s disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing | ORKG Ask

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Additional file 3: of Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia

Melanie Hüttenrauch (5875202)
Isabella Ogorek (528694)
Hans Klafki (1735903)
Markus Otto (120832)
Christine Stadelmann (137943)
Sascha Weggen (185102)
Jens Wiltfang (44073)
Oliver Wirths (3554801)

October 2018

Quantification of Aβ plaque load and GPNMB immunoreactivity in 5XFAD mice. (PDF 434 kb

Additional file 7: of NMDA receptors mediate synaptic depression, but not spine loss in the dentate gyrus of adult amyloid Beta (Aβ) overexpressing mice

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Eric Jacobi (5890610)
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Roberto Malinow (1320306)
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Table S1. mEPSC recordings of CT100-overexpressing DG granule cells. Table S2. Morphological analysi...

Additional file 1 of Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

January 2024

Additional file 1: Fig. S1. Principal component plots of C2 vs C1 using HapMap Phase II as reference...

Additional file 6: Figure S6. of Human neural stem cells alleviate Alzheimer-like pathology in a mouse model

Il-Shin Lee (611843)
Kwangsoo Jung (3421763)
Il-Sun Kim (611842)
Haejin Lee (611840)
Miri Kim (2113432)
Seokhwan Yun (611841)
Kyujin Hwang (3421760)
Jeong Eun Shin (611844)
Kook In Park (486370)

August 2015

NSE/APPsw transgenic mouse-derived brain slices treated with BDNF-depleted CM. (A) Western blot show...

Additional file 3: Figure S3. of Human neural stem cells alleviate Alzheimer-like pathology in a mouse model

Il-Shin Lee (611843)
Kwangsoo Jung (3421763)
Il-Sun Kim (611842)
Haejin Lee (611840)
Miri Kim (2113432)
Seokhwan Yun (611841)
Kyujin Hwang (3421760)
Jeong Eun Shin (611844)
Kook In Park (486370)

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hNSCs express diverse trophic factors. (A) In vitro proliferating and differentiated hNSCs expressed...

Additional file 1: Figure S1. of Human neural stem cells alleviate Alzheimer-like pathology in a mouse model

Il-Shin Lee (611843)
Kwangsoo Jung (3421763)
Il-Sun Kim (611842)
Haejin Lee (611840)
Miri Kim (2113432)
Seokhwan Yun (611841)
Kyujin Hwang (3421760)
Jeong Eun Shin (611844)
Kook In Park (486370)

August 2015

GFP expression by lenti-GFP-transduced hNSCs. Proliferating lenti-GFP-transduced hNSCs form neurosph...

Additional file 1: Supplemental figures. of Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics

Francis Aguisanda (4181743)
Charles Yeh (4181746)
Catherine Chen (3247986)
Rong Li (72042)
Jeanette Beers (4181749)
Jizhong Zou (683547)
Natasha Thorne (105050)
Wei Zheng (25452)

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Figure S1.Â Immunocytochemical characterization of WD iPSCs. Figure S2. STR DNA analysis of WD fibro...

Additional file 7: of Glycoprotein NMB: a novel Alzheimerâs disease associated marker expressed in a subset of activated microglia

Melanie HĂźttenrauch (5875208)
Isabella Ogorek (528694)
Hans Klafki (1735903)
Markus Otto (120832)
Christine Stadelmann (137943)
Sascha Weggen (185102)
Jens Wiltfang (44073)
Oliver Wirths (3554801)

October 2018

Correlation analysis between GPNMB gene expression levels and microglia markers measured by RT-PCR. ...

Additional file 1: of Alzheimerâs disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph

Lorenza Magno (5152364)
Christian Lessard (6290984)
Marta Martins (69128)
Verena Lang (6290987)
Pedro Cruz (202548)
Yasmine Asi (3523280)
Matilda Katan (441476)
Jamie Bilsland (6290990)
Tammaryn Lashley (3932903)
Paramita Chakrabarty (426637)
Todd Golde (337754)
Paul Whiting (3506147)

February 2019

Plcg2 in situ hybridization on brain tissue. A) RNAScope for PLCG2, positive (PPIB) and negative (Da...

Additional file 3: Figure S3. of MH84 improves mitochondrial dysfunction in a mouse model of early Alzheimer’s disease

Maximilian Pohland (4392025)
Maren Pellowska (4848289)
Heike Asseburg (4848298)
Stephanie Hagl (3482792)
Martina Reutzel (4848292)
Aljoscha Joppe (4848295)
Dirk Berressem (1987069)
Schamim Eckert (4848286)
Mario Wurglics (1373676)
Manfred Schubert‐Zsilavecz (4848283)
Gunter Eckert (3482789)

February 2018

Western blot analysis of A brain-derived neurotrophic factor (BDNF), B Growth associated protein 43 ...

Additional file 8: of Chronic adiponectin deficiency leads to Alzheimer’s disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice

Roy Ng (3539159)
On-Yin Cheng (291737)
Min Jian (394957)
Jason Kwan (164198)
Philip Ho (3539171)
Kenneth Cheng (1604182)
Patrick Yeung (3539162)
Lena Zhou (3539168)
Ruby Hoo (3539174)
Sookja Chung (261115)
Aimin Xu (120142)
Karen Lam (3434780)
Koon Chan (3539165)

November 2016

APN enhances insulin sensitivity in neuronal cells with insulin resistance. SH-SY5Y neuroblastoma ce...

Additional file 5: of Glycoprotein NMB: a novel Alzheimerâs disease associated marker expressed in a subset of activated microglia

Melanie HĂźttenrauch (5875208)
Isabella Ogorek (528694)
Hans Klafki (1735903)
Markus Otto (120832)
Christine Stadelmann (137943)
Sascha Weggen (185102)
Jens Wiltfang (44073)
Oliver Wirths (3554801)

October 2018

Correlation analysis between GPNMB-ELISA (TBS- and SDS-soluble fractions) and GPNMB expression level...

Additional file 1: of Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress

Shengchun Xu (5060504)
Zemin Di (6332741)
Yufeng He (5673119)
Runjie Wang (6332744)
Yuyang Ma (3695131)
Rui Sun (177521)
Jing Li (10611)
Tao Wang (12008)
Yujun Shen (3412115)
Shengyun Fang (207485)
Lijie Feng (3412118)
Yuxian Shen (454391)

February 2019

Figure S1. Aβ1–42 induces ER stress and upregulates MANF expression in primarily cultured rat neuron...

Additional file 3: of Expression of the neuroprotective protein aryl hydrocarbon receptor nuclear translocator 2 correlates with neuronal stress and disability in models of multiple sclerosis

Tissa Rahim (5771639)
Pierre Becquart (184034)
Maria-Elizabeth Baeva (5771642)
Jacqueline Quandt (3586649)

September 2018

Table S3. Primary enriched neuronal cortical cultures have few glial cells. Breakdown of culture pur...

Additional file 1: of The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

Nicholas Vogt (6114617)
Kymberleigh Romano (5118683)
Burcu Darst (6114620)
Corinne Engelman (6114623)
Sterling Johnson (570977)
Cynthia Carlsson (6114626)
Sanjay Asthana (72430)
Kaj Blennow (58615)
Henrik Zetterberg (144718)
Barbara Bendlin (6114629)
Federico Rey (5237288)

December 2018

Methods. Additional details from Metabolon for methodology of CSF TMAO quantification. Figure S1. Re...

Additional file 3: of Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia

Melanie Hüttenrauch (5875202)
Isabella Ogorek (528694)
Hans Klafki (1735903)
Markus Otto (120832)
Christine Stadelmann (137943)
Sascha Weggen (185102)
Jens Wiltfang (44073)
Oliver Wirths (3554801)

October 2018

Quantification of Aβ plaque load and GPNMB immunoreactivity in 5XFAD mice. (PDF 434 kb

Additional file 7: of NMDA receptors mediate synaptic depression, but not spine loss in the dentate gyrus of adult amyloid Beta (Aβ) overexpressing mice

Michaela Müller (77210)
Eric Jacobi (5890610)
Kenji Sakimura (47744)
Roberto Malinow (1320306)
Jakob von Engelhardt (5890616)

October 2018

Table S1. mEPSC recordings of CT100-overexpressing DG granule cells. Table S2. Morphological analysi...

Additional file 1 of Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

January 2024

Additional file 1: Fig. S1. Principal component plots of C2 vs C1 using HapMap Phase II as reference...

Additional file 6: Figure S6. of Human neural stem cells alleviate Alzheimer-like pathology in a mouse model

Il-Shin Lee (611843)
Kwangsoo Jung (3421763)
Il-Sun Kim (611842)
Haejin Lee (611840)
Miri Kim (2113432)
Seokhwan Yun (611841)
Kyujin Hwang (3421760)
Jeong Eun Shin (611844)
Kook In Park (486370)

August 2015

NSE/APPsw transgenic mouse-derived brain slices treated with BDNF-depleted CM. (A) Western blot show...

Additional file 3: Figure S3. of Human neural stem cells alleviate Alzheimer-like pathology in a mouse model

Il-Shin Lee (611843)
Kwangsoo Jung (3421763)
Il-Sun Kim (611842)
Haejin Lee (611840)
Miri Kim (2113432)
Seokhwan Yun (611841)
Kyujin Hwang (3421760)
Jeong Eun Shin (611844)
Kook In Park (486370)

August 2015

hNSCs express diverse trophic factors. (A) In vitro proliferating and differentiated hNSCs expressed...

Additional file 1: Figure S1. of Human neural stem cells alleviate Alzheimer-like pathology in a mouse model

Il-Shin Lee (611843)
Kwangsoo Jung (3421763)
Il-Sun Kim (611842)
Haejin Lee (611840)
Miri Kim (2113432)
Seokhwan Yun (611841)
Kyujin Hwang (3421760)
Jeong Eun Shin (611844)
Kook In Park (486370)

August 2015

GFP expression by lenti-GFP-transduced hNSCs. Proliferating lenti-GFP-transduced hNSCs form neurosph...

Additional file 1: Supplemental figures. of Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics

Francis Aguisanda (4181743)
Charles Yeh (4181746)
Catherine Chen (3247986)
Rong Li (72042)
Jeanette Beers (4181749)
Jizhong Zou (683547)
Natasha Thorne (105050)
Wei Zheng (25452)

June 2017

Figure S1.Â Immunocytochemical characterization of WD iPSCs. Figure S2. STR DNA analysis of WD fibro...

Additional file 7: of Glycoprotein NMB: a novel Alzheimerâs disease associated marker expressed in a subset of activated microglia

Melanie HĂźttenrauch (5875208)
Isabella Ogorek (528694)
Hans Klafki (1735903)
Markus Otto (120832)
Christine Stadelmann (137943)
Sascha Weggen (185102)
Jens Wiltfang (44073)
Oliver Wirths (3554801)

October 2018

Correlation analysis between GPNMB gene expression levels and microglia markers measured by RT-PCR. ...

Additional file 1: of Alzheimerâs disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph

Lorenza Magno (5152364)
Christian Lessard (6290984)
Marta Martins (69128)
Verena Lang (6290987)
Pedro Cruz (202548)
Yasmine Asi (3523280)
Matilda Katan (441476)
Jamie Bilsland (6290990)
Tammaryn Lashley (3932903)
Paramita Chakrabarty (426637)
Todd Golde (337754)
Paul Whiting (3506147)

February 2019

Plcg2 in situ hybridization on brain tissue. A) RNAScope for PLCG2, positive (PPIB) and negative (Da...

Additional file 3: Figure S3. of MH84 improves mitochondrial dysfunction in a mouse model of early Alzheimer’s disease

Maximilian Pohland (4392025)
Maren Pellowska (4848289)
Heike Asseburg (4848298)
Stephanie Hagl (3482792)
Martina Reutzel (4848292)
Aljoscha Joppe (4848295)
Dirk Berressem (1987069)
Schamim Eckert (4848286)
Mario Wurglics (1373676)
Manfred Schubert‐Zsilavecz (4848283)
Gunter Eckert (3482789)

February 2018

Western blot analysis of A brain-derived neurotrophic factor (BDNF), B Growth associated protein 43 ...

Additional file 8: of Chronic adiponectin deficiency leads to Alzheimer’s disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice

Roy Ng (3539159)
On-Yin Cheng (291737)
Min Jian (394957)
Jason Kwan (164198)
Philip Ho (3539171)
Kenneth Cheng (1604182)
Patrick Yeung (3539162)
Lena Zhou (3539168)
Ruby Hoo (3539174)
Sookja Chung (261115)
Aimin Xu (120142)
Karen Lam (3434780)
Koon Chan (3539165)

November 2016

APN enhances insulin sensitivity in neuronal cells with insulin resistance. SH-SY5Y neuroblastoma ce...

Additional file 5: of Glycoprotein NMB: a novel Alzheimerâs disease associated marker expressed in a subset of activated microglia

Melanie HĂźttenrauch (5875208)
Isabella Ogorek (528694)
Hans Klafki (1735903)
Markus Otto (120832)
Christine Stadelmann (137943)
Sascha Weggen (185102)
Jens Wiltfang (44073)
Oliver Wirths (3554801)

October 2018

Correlation analysis between GPNMB-ELISA (TBS- and SDS-soluble fractions) and GPNMB expression level...

Additional file 1: of Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress

Shengchun Xu (5060504)
Zemin Di (6332741)
Yufeng He (5673119)
Runjie Wang (6332744)
Yuyang Ma (3695131)
Rui Sun (177521)
Jing Li (10611)
Tao Wang (12008)
Yujun Shen (3412115)
Shengyun Fang (207485)
Lijie Feng (3412118)
Yuxian Shen (454391)

February 2019

Figure S1. Aβ1–42 induces ER stress and upregulates MANF expression in primarily cultured rat neuron...

Additional file 3: of Expression of the neuroprotective protein aryl hydrocarbon receptor nuclear translocator 2 correlates with neuronal stress and disability in models of multiple sclerosis

Tissa Rahim (5771639)
Pierre Becquart (184034)
Maria-Elizabeth Baeva (5771642)
Jacqueline Quandt (3586649)

September 2018

Table S3. Primary enriched neuronal cortical cultures have few glial cells. Breakdown of culture pur...

Additional file 1: of The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

Nicholas Vogt (6114617)
Kymberleigh Romano (5118683)
Burcu Darst (6114620)
Corinne Engelman (6114623)
Sterling Johnson (570977)
Cynthia Carlsson (6114626)
Sanjay Asthana (72430)
Kaj Blennow (58615)
Henrik Zetterberg (144718)
Barbara Bendlin (6114629)
Federico Rey (5237288)

December 2018

Methods. Additional details from Metabolon for methodology of CSF TMAO quantification. Figure S1. Re...

Additional file 3: of Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia

Melanie Hüttenrauch (5875202)
Isabella Ogorek (528694)
Hans Klafki (1735903)
Markus Otto (120832)
Christine Stadelmann (137943)
Sascha Weggen (185102)
Jens Wiltfang (44073)
Oliver Wirths (3554801)

October 2018

Quantification of Aβ plaque load and GPNMB immunoreactivity in 5XFAD mice. (PDF 434 kb

Additional file 7: of NMDA receptors mediate synaptic depression, but not spine loss in the dentate gyrus of adult amyloid Beta (Aβ) overexpressing mice

Michaela Müller (77210)
Eric Jacobi (5890610)
Kenji Sakimura (47744)
Roberto Malinow (1320306)
Jakob von Engelhardt (5890616)

October 2018

Table S1. mEPSC recordings of CT100-overexpressing DG granule cells. Table S2. Morphological analysi...

Additional file 1 of Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

January 2024

Additional file 1: Fig. S1. Principal component plots of C2 vs C1 using HapMap Phase II as reference...