Figure S1. Diagnostic and prognostic ability of ProCUrE and age-adjusted PSA in the training cohort. Figure S2. Receiver operating characteristic curve analysis of training cohort for (A) benign vs PCa, clinically insignificant vs clinically significant PCa as determined by (B) GS, (C) CAPRA, and (D) DâAmico. (DOCX 291 kb
Figure S5. Flow diagram of participants in the cross-sectional study according a) to the three-gene ...
Hierarchical cluster of 50 paired normal and tumor tissue of PrCa patients from TCGA-PRAD dataset. A...
Sample purity. Figure S2. Sample dissimilarity. Figure S3. Unsupervised clustering and heatmaps. Fig...
Table S1. Correlations. Spearman’s rank correlations for the PMR values of each biomarker, ProCUrE, ...
Figure S1. Box-plots of panel #1 (miR-34b/c, miR-193b) and panel #2 (APC, GSTP1, and RARβ2) promoter...
Table S1. Primer sequences for β-Actin, miR-34b/c, and miR-193b (panel #1). Table S2. Scorpion prime...
Figure S2. Box-plots of panel #1 (miR-34b/c, miR-193b) and panel #2 (APC, RARβ2) promoter methylatio...
Table S1. Results of modeling using continuous and binary methylation levels. Table S2. the range of...
ROC curve and waterfall plot for the top hypermethylated CpG model in the TCGA validation cohort (a-...
In silico analysis of TCGA data correlating DNA methylation and mRNA expression of commonly methylat...
Table S1. Primer and probe sequences used for CRISPR verification and methylation-specific qPCR. (XL...
ROC curve and waterfall plot for diagnostic model applied to an independent cohort of prostate cance...
Figure S8. X-tile analysis and Kaplan-Meier plots for prediction of biochemical recurrence-free surv...
Boxplots of CpGs in the top diagnostic model from hypermethylated CpGs. Normal data is from benign-a...
Table S3. List of CpG islands included in the biomarker panel. Table S4. List of primers and probes....
Figure S5. Flow diagram of participants in the cross-sectional study according a) to the three-gene ...
Hierarchical cluster of 50 paired normal and tumor tissue of PrCa patients from TCGA-PRAD dataset. A...
Sample purity. Figure S2. Sample dissimilarity. Figure S3. Unsupervised clustering and heatmaps. Fig...
Table S1. Correlations. Spearman’s rank correlations for the PMR values of each biomarker, ProCUrE, ...
Figure S1. Box-plots of panel #1 (miR-34b/c, miR-193b) and panel #2 (APC, GSTP1, and RARβ2) promoter...
Table S1. Primer sequences for β-Actin, miR-34b/c, and miR-193b (panel #1). Table S2. Scorpion prime...
Figure S2. Box-plots of panel #1 (miR-34b/c, miR-193b) and panel #2 (APC, RARβ2) promoter methylatio...
Table S1. Results of modeling using continuous and binary methylation levels. Table S2. the range of...
ROC curve and waterfall plot for the top hypermethylated CpG model in the TCGA validation cohort (a-...
In silico analysis of TCGA data correlating DNA methylation and mRNA expression of commonly methylat...
Table S1. Primer and probe sequences used for CRISPR verification and methylation-specific qPCR. (XL...
ROC curve and waterfall plot for diagnostic model applied to an independent cohort of prostate cance...
Figure S8. X-tile analysis and Kaplan-Meier plots for prediction of biochemical recurrence-free surv...
Boxplots of CpGs in the top diagnostic model from hypermethylated CpGs. Normal data is from benign-a...
Table S3. List of CpG islands included in the biomarker panel. Table S4. List of primers and probes....
Figure S5. Flow diagram of participants in the cross-sectional study according a) to the three-gene ...
Hierarchical cluster of 50 paired normal and tumor tissue of PrCa patients from TCGA-PRAD dataset. A...
Sample purity. Figure S2. Sample dissimilarity. Figure S3. Unsupervised clustering and heatmaps. Fig...