Additional file 11: of GM604 regulates developmental neurogenesis pathways and the expression of genes associated with amyotrophic lateral sclerosis

DNA motifs enriched in sequences upstream of GM6-increased genes. (A – D) Figures show motifs enriched in 5000 bp regions upstream of genes increased by GM6 at (A) 6 h, (B) 24 h, (C) 48 h and (D) 6–48 h (FDR < 0.10). Motif labels and consensus sequences are listed in the left margin. Red font is used for motifs known to interact with a protein encoded by a GM6-increased gene (P < 0.05), and blue font used for motifs known to interact with a protein encoded by a GM6-decreased gene (P < 0.05). Sequence logos for the top-ranked 12 motifs are shown for each time point. (TIF 2072 kb