(A) Schematic depiction of the in-contact challenge assay. The black box indicates a separate room. Different colours indicate different types of pigs. Each room included one non-TG pig that was injected with CSFV (NTG-In), three NTG pigs and three TG pigs. (B) Mortality and viremia in challenged pigs. The survival time of each pig is indicated by the length of the green bar. Red squares indicate the collection of blood samples. The terminal block colour indicates day and cause of death (black, found dead; blue, pigs (TG-4 and TG-5) euthanized for comparison to the dead NTG pig). The numbers for each day are the lg values of viral RNA copies present in the blood samples.</p
<p>SIC: small intestinal contents; LIC: large intestinal contents euthanasia. Horizontal bars repres...
Well-defined pig models are useful to study the pathogenicity of newly recognized pathogens or strai...
<p>(a) The figure depicts representative photographs of lungs, spleen and liver of guinea pigs belon...
(A) Survival curves of the challenged pigs during in-contact infection. Different curves indicate di...
<p>(A) Survival curves for the pigs in the two challenged groups after infection with PRRSV JXA1. Th...
<p>Pigs were vaccinated with C-strain CSFV on days -5, -3 or -1 and were then challenged, together w...
<p>(A) Rectal temperature was recorded everyday post-challenge (day -1 to 7). SwIV titer in BAL flui...
<p>Continuous lines represent geometric mean of porcine IgG Ab titers (GMT) to the corresponding tre...
<p>All animals were orally inoculated at 72 h of age [0 post inoculation day (0 PID)], and euthanize...
<p>(A) Total nucleated-cell counting using whole blood samples taken at different days after ASFV ch...
<p>Bold areas indicate the pigs experimentally inoculated with PEDV.</p>1<p>Number of pigs affected/...
<p>Each pig is represented by a circle, numbered by index. Arrows between pigs represent potential t...
<p>Samples were chosen to represent different pig species (wild boar, domestic pigs) and inoculation...
<p>Pigs were unvaccinated or vaccinated as indicated and challenged with PRRSV MN184 and euthanized ...
A) Comparison of the total viral loads on days 1, 2, and 3 DPI visualized as the median area under t...
<p>SIC: small intestinal contents; LIC: large intestinal contents euthanasia. Horizontal bars repres...
Well-defined pig models are useful to study the pathogenicity of newly recognized pathogens or strai...
<p>(a) The figure depicts representative photographs of lungs, spleen and liver of guinea pigs belon...
(A) Survival curves of the challenged pigs during in-contact infection. Different curves indicate di...
<p>(A) Survival curves for the pigs in the two challenged groups after infection with PRRSV JXA1. Th...
<p>Pigs were vaccinated with C-strain CSFV on days -5, -3 or -1 and were then challenged, together w...
<p>(A) Rectal temperature was recorded everyday post-challenge (day -1 to 7). SwIV titer in BAL flui...
<p>Continuous lines represent geometric mean of porcine IgG Ab titers (GMT) to the corresponding tre...
<p>All animals were orally inoculated at 72 h of age [0 post inoculation day (0 PID)], and euthanize...
<p>(A) Total nucleated-cell counting using whole blood samples taken at different days after ASFV ch...
<p>Bold areas indicate the pigs experimentally inoculated with PEDV.</p>1<p>Number of pigs affected/...
<p>Each pig is represented by a circle, numbered by index. Arrows between pigs represent potential t...
<p>Samples were chosen to represent different pig species (wild boar, domestic pigs) and inoculation...
<p>Pigs were unvaccinated or vaccinated as indicated and challenged with PRRSV MN184 and euthanized ...
A) Comparison of the total viral loads on days 1, 2, and 3 DPI visualized as the median area under t...
<p>SIC: small intestinal contents; LIC: large intestinal contents euthanasia. Horizontal bars repres...
Well-defined pig models are useful to study the pathogenicity of newly recognized pathogens or strai...
<p>(a) The figure depicts representative photographs of lungs, spleen and liver of guinea pigs belon...